Evidence map›Paper›PMID 33458343›Full record

ArticlePhysics and imaging in radiation oncology2020

A study to investigate the influence of cardiac motion on the robustness of pencil beam scanning proton plans in oesophageal cancer.

Melissa Thomas, Gilles Defraene, Mario Levis, Edmond Sterpin, Maarten Lambrecht, Umberto Ricardi, Karin Haustermans

Abstract read
In one paragraph

Article in Physics and imaging in radiation oncology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Melissa ThomasKU Leuven - University of Leuven, Department of Oncology - Laboratory Experimental Radiotherapy, Leuven, Belgium.
Gilles DefraeneKU Leuven - University of Leuven, Department of Oncology - Laboratory Experimental Radiotherapy, Leuven, Belgium.
Mario LevisUniversity of Torino, Department of Oncology, Torino, Italy.
Edmond SterpinKU Leuven - University of Leuven, Department of Oncology - Laboratory Experimental Radiotherapy, Leuven, Belgium.
Maarten LambrechtKU Leuven - University of Leuven, Department of Oncology - Laboratory Experimental Radiotherapy, Leuven, Belgium.
Umberto RicardiUniversity of Torino, Department of Oncology, Torino, Italy.
Karin HaustermansKU Leuven - University of Leuven, Department of Oncology - Laboratory Experimental Radiotherapy, Leuven, Belgium.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

While proton therapy offers an excellent dose conformity and sparing of organs at risk, this can be compromised by uncertainties, e.g. organ motion. This study aimed to investigate the influence of cardiac motion on the contoured oesophagus using electrocardiogram-triggered imaging and to assess the impact of this motion on the robustness of proton therapy plans in oesophageal cancer patients. Limited cardiac-induced motion of the oesophagus was observed with a negligible impact on the robustness of proton therapy plans. Therefore, our data suggest that cardiac motion may be safely ignored in the robust optimisation strategy for proton planning in oesophageal cancer.

Indexed as

Cardiac motionOesophageal cancerProton therapy

Identifiers

PMID33458343
PMCPMC7807867

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.