ArticlePhysics and imaging in radiation oncology2020
Delivered dose quantification in prostate radiotherapy using online 3D cine imaging and treatment log files on a combined 1.5T magnetic resonance imaging and linear accelerator system.
Article in Physics and imaging in radiation oncology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
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Who cites it
34 citing papers in PubMed.
- Impact of intra- and interfractional motion on the dose distribution and urinary adverse events for magnetic resonance-guided prostate cancer radiotherapy.Physics and imaging in radiation oncology · 2026Article
- Development and evaluation of deep learning models for estimating the organ at-risk dose constraint from two-dimensional cine magnetic resonance imaging scans during irradiation.Journal of applied clinical medical physics · 2025Article
- Intra-adaptational changes in online adaptive radiotherapy: from the ideal to the real dose.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2025Article
- First experimental demonstration of magnetic resonance-guided multileaf collimator tracking for (ultra-)hypofractionated prostate radiotherapy.Physics and imaging in radiation oncology · 2025Article
- Workflow to detect exceeded dose constraints in pancreatic stereotactic body irradiation after intrafraction motion during magnetic resonance-guided adaptive radiotherapy using a deep learning-refined contour propagation tool.Physics and imaging in radiation oncology · 2025Article
- Prostate motion in magnetic resonance imaging-guided radiotherapy and its impact on margins.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2025Article
- Comparison of online adaptation strategies for magnetic resonance guided prostate radiation therapy.Physics and imaging in radiation oncology · 2025Article
- Automated daily dose accumulation workflow for treatment quality assurance during online adaptive radiotherapy with a 0.35T MR-linac.Journal of applied clinical medical physics · 2025Article
- Added value of non-rigid image registration for intrafraction dose accumulation in magnetic resonance imaging-guided prostate radiotherapy.Physics and imaging in radiation oncology · 2025Article
- Treatment planning evaluation and experimental validation of the magnetic resonance-based intrafraction drift correction.Physics and imaging in radiation oncology · 2024Article
- Adaptive Radiotherapy: Next-Generation Radiotherapy.Cancers · 2024Review
- Adaptive ultra-hypofractionated whole-pelvic radiotherapy in high-risk and very high-risk prostate cancer on 1.5-Tesla MR-Linac: Estimated delivered dose and early toxicity results.Chronic diseases and translational medicine · 2024Article
- The Use of MR-Guided Radiation Therapy for Head and Neck Cancer and Recommended Reporting Guidance.Seminars in radiation oncology · 2024Review
- Impact of daily plan adaptation on accumulated doses in ultra-hypofractionated magnetic resonance-guided radiation therapy of prostate cancer.Physics and imaging in radiation oncology · 2024Article
- Investigation of autosegmentation techniques on T2-weighted MRI for off-line dose reconstruction in MR-linac workflow for head and neck cancers.Medical physics · 2024Article
- Evaluation of Unity 1.5 T MR-linac plan quality in patients with prostate cancer.Journal of applied clinical medical physics · 2023Article
- Experimental validation of multi-fraction online adaptations in magnetic resonance guided radiotherapy.Physics and imaging in radiation oncology · 2023Article
- Assessment of intrafractional prostate motion and its dosimetric impact in MRI-guided online adaptive radiotherapy with gating.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2023Article
- Applicability and usage of dose mapping/accumulation in radiotherapy.Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology · 2023Review
- Assessment of delivered dose in prostate cancer patients treated with ultra-hypofractionated radiotherapy on 1.5-Tesla MR-Linac.Frontiers in oncology · 2023Article
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Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
background and purposeMonitoring the intrafraction motion and its impact on the planned dose distribution is of crucial importance in radiotherapy. In this work we quantify the delivered dose for the first prostate patients treated on a combined 1.5T Magnetic Resonance Imaging (MRI) and linear accelerator system in our clinic based on online 3D cine-MR and treatment log files. MATERIALS AND
methodsA prostate intrafraction motion trace was obtained with a soft-tissue based rigid registration method with six degrees of freedom from 3D cine-MR dynamics with a temporal resolution of 8.5-16.9 s. For each fraction, all dynamics were also registered to the daily MR image used during the online treatment planning, enabling the mapping to this reference point. Moreover, each fraction's treatment log file was used to extract the timestamped machine parameters during delivery and assign it to the appropriate dynamic volume. These partial plans to dynamic volume combinations were calculated and summed to yield the delivered fraction dose. The planned and delivered dose distributions were compared among all patients for a total of 100 fractions.
resultsThe clinical target volume underwent on average a decrease of 2.2% ± 2.9% in terms of D99% coverage while bladder V62Gy was increased by 1.6% ± 2.3% and rectum V62Gy decreased by 0.2% ± 2.2%.
conclusionsThe first MR-linac dose reconstruction results based on prostate tracking from intrafraction 3D cine-MR and treatment log files are presented. Such a pipeline is essential for online adaptation especially as we progress to MRI-guided extremely hypofractionated treatments.
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