ArticlePhysics and imaging in radiation oncology2019
A preferred patient decubitus positioning for magnetic resonance image guided online adaptive radiation therapy of pancreatic cancer.
Article in Physics and imaging in radiation oncology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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- Functional hydrogel empowering 3D printing titanium alloys.Materials today. Bio · 2025Review
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9 authors at 2 institutions in 2 countries.
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No grant is acknowledged in the PubMed record.
Abstract
background and purposeIn radiotherapy (RT) for pancreatic cancer, the dose to adjacent organs-at-risk (OAR) often limits the delivery of curative dose. This work aimed to find a body decubitus position that would lead to increased separation between the duodenum and pancreatic head. MATERIALS AND
methodsAbdominal magnetic resonance images (MRI) of 11 healthy volunteers were acquired using a 1.5T MR-Linac for supine, left decubitus and right decubitus body positions. The geometry changes between different body positions were measured using Hausdorff Distance (HD) and overlap volume. RT plans were created on the MRIs. Commonly used dose-volume parameters (DVP), e.g., V
resultsThe average of maximum HD between the duodenum and pancreatic head for all the cases was 4.0 ± 3.1 mm for supine, 7.3 ± 4.4 mm for left and 3.3 ± 1.4 mm for right positions (P < 0.01). The DVPs of the duodenum (e.g., V
conclusionThe left decubitus increased the separation between duodenum and pancreas head, improving OAR sparing in RT for pancreatic cancer and allowing safer dose escalations to the tumor. The left decubitus positioning with proper immobilization could be adopted for MRI-guided adaptive RT.
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