Evidence map›Paper›PMID 33458269›Full record

ArticlePhysics and imaging in radiation oncology2019

Assessment of dosimetric and positioning accuracy of a magnetic resonance imaging-only solution for external beam radiotherapy of pelvic anatomy.

Reko Kemppainen, Sami Suilamo, Iiro Ranta, Marko Pesola, Aleksi Halkola, Alvin Eufemio, Heikki Minn, Jani Keyriläinen

Open access · goldAbstract read
In one paragraph

Article in Physics and imaging in radiation oncology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
5.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 31 citations in OpenAlex.

  1. Article
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  5. The use of PET/MRI in radiotherapy.Insights into imaging · 2024
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  9. Clinical rationale forPhysics and imaging in radiation oncology · 2022
    Article
  10. Article
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  13. Article
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  15. Article
  16. Multicentre, deep learning, synthetic-CT generation for ano-rectal MR-only radiotherapy treatment planning.Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology · 2021
    Article
  17. Article
  18. Article
  19. Article
  20. Imaging science and development in modern high-precision radiotherapy.Physics and imaging in radiation oncology · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Reko KemppainenPhilips Oy, Äyritie 4, FI-01510 Vantaa, Finland.
Sami SuilamoDepartment of Medical Physics, Turku University Hospital, Hämeentie 11, P.O. Box 52, FI-20521 Turku, Finland.
Iiro RantaDepartment of Medical Physics, Turku University Hospital, Hämeentie 11, P.O. Box 52, FI-20521 Turku, Finland.
Marko PesolaPhilips Oy, Äyritie 4, FI-01510 Vantaa, Finland.
Aleksi HalkolaPhilips Oy, Äyritie 4, FI-01510 Vantaa, Finland.
Alvin EufemioPhilips Oy, Äyritie 4, FI-01510 Vantaa, Finland.
Heikki MinnDepartment of Oncology and Radiotherapy, Turku University Hospital, Hämeentie 11, P.O. Box 52, FI-20521 Turku, Finland.
Jani KeyriläinenDepartment of Medical Physics, Turku University Hospital, Hämeentie 11, P.O. Box 52, FI-20521 Turku, Finland.
Philips (Finland) · FITurku University Hospital · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeThe clinical feasibility of synthetic computed tomography (sCT) images derived from magnetic resonance imaging (MRI) images for external beam radiation therapy (EBRT) planning have been studied and adopted into clinical use recently. This paper evaluates the dosimetric and positioning performance of a sCT approach for different pelvic cancers. MATERIALS AND

methodsSeventy-five patients receiving EBRT at Turku University Hospital (Turku, Finland) were enrolled in the study. The sCT images were generated as part of a clinical MRI-simulation procedure. Dose calculation accuracy was assessed by comparing the sCT-based calculation with a CT-based calculation. In addition, we evaluated the patient position verification accuracy for both digitally reconstructed radiograph (DRR) and cone beam computed tomography (CBCT) -based image guidance using a subset of the cohort. Furthermore, the relevance of using continuous Hounsfield unit values was assessed.

resultsThe mean (standard deviation) relative dose difference in the planning target volume mean dose computed over various cancer groups was less than 0.2 (0.4)% between sCT and CT. Among all groups, the average minimum gamma-index pass-rates were better than 95% with a 2%/2mm gamma-criteria. The difference between sCT- and CT-DRR-based patient positioning was less than 0.3 (1.4) mm in all directions. The registrations of sCT to CBCT produced similar results as compared with CT to CBCT registrations.

conclusionsThe use of sCT for clinical EBRT dose calculation and patient positioning in the investigated types of pelvic cancers was dosimetrically and geometrically accurate for clinical use.

Indexed as

Image-guided radiotherapyMRI-onlyPosition verificationRadiotherapy

Identifiers

PMID33458269
PMCPMC7807675
OpenAlexW2950030460

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.