Evidence map›Paper›PMID 33457414›Full record

ArticleBioMed research international2020

The Survival Advantage of Females at Premenopausal Age Is Race Dependent in Colorectal Cancer.

Hui Sheng, Xiaoli Wei, Qunxi Chen, Kewei Huang, Runkun Han, Yijun Liu, Wen Liu, Minjie Mao

Open access · hybridAbstract read
In one paragraph

Article in BioMed research international, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Hui ShengDepartment of Experimental Research, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou 510060, China.ORCID https://orcid.org/0000-0002-2040-8842
Xiaoli WeiDepartment of Medical Oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou 510060, China.ORCID https://orcid.org/0000-0001-8414-4957
Qunxi ChenDepartment of Pathology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou 510060, China.ORCID https://orcid.org/0000-0002-2038-8597
Kewei HuangDepartment of Clinical Laboratory, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou 510060, China.ORCID https://orcid.org/0000-0003-3753-3479
Runkun HanDepartment of Clinical Laboratory, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou 510060, China.ORCID https://orcid.org/0000-0001-9220-6417
Yijun LiuDepartment of Clinical Laboratory, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou 510060, China.ORCID https://orcid.org/0000-0001-7780-8866
Wen LiuDepartment of Clinical Laboratory, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou 510060, China.ORCID https://orcid.org/0000-0002-7418-2543
Minjie MaoDepartment of Clinical Laboratory, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou 510060, China.ORCID https://orcid.org/0000-0002-5250-8186
Sun Yat-sen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundA female prognostic advantage in younger individuals has been demonstrated in various cancers. Several large-scale analyses based on different racial backgrounds have reported inconsistent results in colorectal cancer. The aim of the present study was to evaluate the prognostic value of sex and age in patients with colorectal cancer of different ethnic groups.

methodsWe identified 71,812 eligible patients from the Surveillance, Epidemiology and End Results database. According to age at diagnosis, the patients were categorized into premenopausal age (≤45 yrs), menopausal age (46-54 yrs), and postmenopausal age (≥55 yrs) subgroups for further analysis.

resultsMultivariate analysis identified the female survival advantage to be significant in the premenopausal age subgroup (

conclusionsSex was a major prognostic factor in colorectal cancer patients, especially premenopausal women, and the difference was also associated with race.

Indexed as

EthnicityAdultBlack or African AmericanColorectal NeoplasmsFemaleHumansMaleMenopauseMiddle AgedMultivariate AnalysisPostmenopausePremenopausePrognosisSEER ProgramUnited StatesWhite People

Identifiers

PMID33457414
PMCPMC7787739
OpenAlexW3114969917

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.