Evidence map›Paper›PMID 33457403›Full record

ArticleBioMed research international2020

Identification of the Functional Domain of HPIV3 Matrix Protein Interacting with Nucleocapsid Protein.

Xichuan Deng, Chaoliang Zhang, Kehan Zhang, Nan Lu, Yonglin He, Jia Liu, Zhibang Yang, Guangyuan Zhang

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BioMed research international, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 78% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Xichuan DengPathogen Biology and Immunology Laboratory, Tissue and Cell Biology Laboratory, Experimental Teaching Management Center, Chongqing Medical University, Chongqing 401331, China.ORCID https://orcid.org/0000-0002-7836-8708
Chaoliang ZhangThe First Clinical College of Chongqing Medical University, Chongqing 401331, China.ORCID https://orcid.org/0000-0002-2215-6183
Kehan ZhangThe First Clinical College of Chongqing Medical University, Chongqing 401331, China.ORCID https://orcid.org/0000-0003-2889-6534
Nan LuDepartment of Pathogen Biology, Basic Medical College of Chongqing Medical University, Chongqing 401331, China.ORCID https://orcid.org/0000-0002-3056-7871
Yonglin HeDepartment of Pathogen Biology, Basic Medical College of Chongqing Medical University, Chongqing 401331, China.ORCID https://orcid.org/0000-0002-6501-7685
Jia LiuPathogen Biology and Immunology Laboratory, Tissue and Cell Biology Laboratory, Experimental Teaching Management Center, Chongqing Medical University, Chongqing 401331, China.ORCID https://orcid.org/0000-0001-8748-6346
Zhibang YangPathogen Biology and Immunology Laboratory, Tissue and Cell Biology Laboratory, Experimental Teaching Management Center, Chongqing Medical University, Chongqing 401331, China.ORCID https://orcid.org/0000-0002-9729-5153
Guangyuan ZhangPathogen Biology and Immunology Laboratory, Tissue and Cell Biology Laboratory, Experimental Teaching Management Center, Chongqing Medical University, Chongqing 401331, China.ORCID https://orcid.org/0000-0002-8079-8360
Chongqing Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human parainfluenza virus type 3 (HPIV3) is the main pathogen that causes respiratory infections in infants, young children, and the elderly. Currently, there are no vaccines and effective anti-infective drugs. Studying the replication and proliferation mechanism of HPIV3 is helpful for exploring the targets of anti-HPIV3 infection. Matrix protein (M) and nucleocapsid protein (N) are two key structural proteins of HPIV3 that exert important functions in HPIV3 proliferation. Herein, we aim to clarify the functional domains of M and N interaction. HPIV3 M and N expression plasmids of pCAGGS-HA-M and pCAGGS-N-Myc/Flag, M C-terminal truncation mutant plasmids of pCAGGSHA-M

Indexed as

Virus ReplicationCell MembraneCytoplasmGene DeletionHEK293 CellsHeLa CellsHumansMicroscopy, FluorescenceNucleocapsid ProteinsParainfluenza Virus 3, HumanPlasmidsProtein BindingProtein DomainsViral Matrix ProteinsNucleocapsid ProteinsViral Matrix Proteins

Identifiers

PMID33457403
PMCPMC7787747
OpenAlexW3112239004

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.