ArticleEuropean journal of case reports in internal medicine2020
Is Persistent Thick Copious Mucus a Long-Term Symptom of COVID-19?
Article in European journal of case reports in internal medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
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Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.
- Post-COVID-19 Syndrome: The Persistent Symptoms at the Post-viral Stage of the Disease. A Systematic Review of the Current Data.Frontiers in medicine · 2021Pooled it
- Maintenance and disruption of mucous barrier homeostasis: the critical role of MUC5AC/MUC5B balance in airway diseases.Frontiers in medicine · 2026Review
- Impact of Nebulized BromAcLife (Basel, Switzerland) · 2024Article
- Chronic airway epithelial hypoxia exacerbates injury in muco-obstructive lung disease through mucus hyperconcentration.Science translational medicine · 2023Article
- Prevalence and Mechanisms of Mucus Accumulation in COVID-19 Lung Disease.American journal of respiratory and critical care medicine · 2022Article
- Mucolytic and Antioxidant Properties of Carbocysteine as a Strategy in COVID-19 Therapy.Life (Basel, Switzerland) · 2022Review
- Genetic alterations, RNA expression profiling and DNA methylation of HMGB1 in malignancies.Journal of cellular and molecular medicine · 2022Article
- Influence of SARS-CoV-2 on airway mucus production: A review and proposed model.Veterinary pathology · 2022Review
- Mucus targeting as a plausible approach to improve lung function in COVID-19 patients.Medical hypotheses · 2021Article
- Evolving phenotypes of non-hospitalized patients that indicate long COVID.BMC medicine · 2021Article
- Challenges in defining Long COVID: Striking differences across literature, Electronic Health Records, and patient-reported information.medRxiv : the preprint server for health sciences · 2021Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionThe typical clinical picture of COVID-19 is gradually becoming clearer, both in the acute phase and in the long-term. However, new symptoms are gradually being identified. We describe a long-term symptom that has not yet been reported. CASE DESCRIPTION: A 49-year-old man consulted for persistent asthenia. The general practitioner found a fever (39.2°C), and COVID-19 was confirmed by the polymerase chain reaction test. Further symptoms appeared, notably thick, white, painless tracheal hypersecretion for 3 months before diminishing, without disappearing.
conclusionNon-inflammatory tracheal hypersecretion, not yet reported in COVID-19, may be an additional long-term symptom. The hyperstimulation of tracheal goblet cells secreting mucus is 1 pathophysiological hypothesis. LEARNING POINTS: Painless, non-inflammatory tracheal hypersecretion, which has yet to be described in post-acute COVID-19, may be an additional long-term symptom of the disease.The hyperstimulation of mucus-secreting tracheal goblet cells by the coronavirus, leading to tracheal discomfort and a feeling of suffocation, is 1 pathophysiological hypothesis.
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