Evidence map›Paper›PMID 33457340›Full record

ArticleAdvanced biomedical research2020

The Effects of Zinc Methionine on Reproductive and Thyroid Hormones in Rats with Polycystic Ovarian Syndrome.

Faeze Fazel Torshizi, Mohammad Chamani, Hamid Reza Khodaei, Ali Asghar Sadeghi, Seyed Hossein Hejazi, Reza Majidzadeh Heravi

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Advanced biomedical research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 8 citations in OpenAlex.

  1. The role of zinc in follicular development.Molecular biology reports · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Faeze Fazel TorshiziDepartment of Animal Science, Science and Research Branch, Islamic Azad University, Tehran, Iran.
Mohammad ChamaniDepartment of Animal Science, Science and Research Branch, Islamic Azad University, Tehran, Iran.
Hamid Reza KhodaeiDepartment of Animal Sciences, Islamic Azad University, Golpayegan Branch, Tehran, Iran.
Ali Asghar SadeghiDepartment of Animal Science, Science and Research Branch, Islamic Azad University, Tehran, Iran.
Seyed Hossein HejaziDepartment of Parasitology and Mycology, Skin Disease and Leishmaniasis Research Center, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
Reza Majidzadeh HeraviDepartment of Animal Sciences, Ferdowsi University of Mashhad, Mashhad, Iran.
Islamic Azad University, Science and Research Branch · IRFerdowsi University of Mashhad · IRIsfahan University of Medical Sciences · IRIslamic Azad University, Isfahan · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPolycystic ovarian syndrome (PCOS) is an endocrine disorder in fertile women, which seems to be adversely affected by associated thyroid dysfunction. Zinc methionine (ZM) has positive effects on PCOS, but its concerted effects on PCOS and thyroid function have not been investigated. We evaluated the effects of ZM on reproductive and thyroid hormones and the number of follicles in rats with PCOS. MATERIALS AND

methodsThis study was conducted on 45 female rats, using sesame oil as control; PCOS animals administered with 0, 25, 75, and 175 mg/kg BW of ZM. Serum concentrations of follicle-stimulating hormone (FSH), luteinizing hormone (LH), and thyroid function were investigated. Premature follicles (PMF), primary follicles (PF), preantral follicles (PAF), antral follicles (AF), corpus luteum (CL), and cystic follicles (CF) were assessed.

resultsPCOS decreased the concentrations of FSH and free T4, but increased the levels of LH, TSH, and LH/FSH ratio (ALL

conclusionsAlthough the induction of PCOS had a negative effect on reproductive and thyroid hormones and follicle numbers, ZM treatment (75 and 175 mg/kg) overcame the negative effects. A high dosage of ZM can alleviate the hormonal and cysts disturbances occurring in PCOS.

Indexed as

Follicle stimulating hormonehormonesovarian folliclepolycystic ovarian syndromeratsthyroid hormoneszinc methionine

Identifiers

PMID33457340
PMCPMC7792867
OpenAlexW3096069518

What OpenQuestion holds

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LicenceCC BY-NC-SA
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.