ArticleTranslational pediatrics2020
Changing trends in the bacteriological profiles and antibiotic susceptibility in neonatal sepsis at a tertiary children's hospital of China.
Article in Translational pediatrics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed, 14 citations in OpenAlex.
- Antimicrobial susceptibility profiles of invasive bacterial infections among children from low- and middle-income countries in the Western Pacific Region (WPRO) - a systematic review and meta-analysis.The Lancet regional health. Western Pacific · 2024Article
- A real-world cost-effectiveness study of vancomycin versus linezolid for the treatment of late-onset neonatal sepsis in the NICU in China.BMC health services research · 2023Article
- [A 10-year retrospective study of pathogens and antimicrobial resistance in neonatal sepsis].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2022Article
- Molecular Epidemiology of Antimicrobial Resistance, Virulence and Capsular Serotypes of Carbapenemase-CarryingAntibiotics (Basel, Switzerland) · 2022Article
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSepsis is a major cause of neonatal morbidity and mortality in developing countries, and early-onset sepsis has poor outcomes. The causative bacteria vary depending on the geographical location of the hospital. This study aimed to determine the changing trends of causative bacteria and antibiotic susceptibility in the past decade.
methodsThis study retrospectively analyzed the blood culture of positive cases of early-onset sepsis admitted to the neonatal intensive care unit of our hospital between 2009 and 2018. The cases were divided into two phases, i.e., phase I (2009 to 2013) and phase II (2014 to 2018). Changing trends in the bacteriological profiles and antibiotic susceptibility were recorded and analyzed.
resultsA total of 1,479 causative bacteria were detected. Gram-positive bacteria were isolated in 74.92% of the cases, and coagulase-negative
conclusionsThe etiological profile of neonatal sepsis (NS) has undergone a significant change in the last decade. Antibiotic resistance has increased, and continuous surveillance for antibiotic susceptibility is required to ensure efficient therapeutic outcomes.
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