Evidence map›Paper›PMID 33457170›Full record

Review3 Biotech2021

Recent biotechnological advances as potential intervention strategies against COVID-19.

Naun Lobo-Galo, Juan-Carlos Gálvez-Ruíz, Ana P Balderrama-Carmona, Norma P Silva-Beltrán, Eduardo Ruiz-Bustos

Abstract readReview
In one paragraph

Review in 3 Biotech, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Naun Lobo-GaloDepartamento de Ciencias Químico Biológicas, Universidad Autónoma de Ciudad Juárez, Ciudad Juárez, Chihuahua Mexico.
Juan-Carlos Gálvez-RuízDepartamento de Ciencias Químico Biológicas, Universidad de Sonora, Hermosillo, Sonora Mexico.
Ana P Balderrama-CarmonaDepartamento de Ciencias Químico Biológicas y Agropecuarias, Unidad Regional Sur, Universidad de Sonora, Navojoa, Sonora Mexico.
Norma P Silva-BeltránDepartamento de Ciencias de la Salud, campus Cajeme, Universidad de Sonora, Ciudad Obregón, Sonora Mexico.ORCID 0000-0001-9360-1283
Eduardo Ruiz-BustosDepartamento de Ciencias Químico Biológicas, Universidad de Sonora, Hermosillo, Sonora Mexico.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The emerging SARS-CoV-2 viral disease (COVID-19) has caused a global health alert due to its high rate of infection and mortality in individuals with chronic cardiovascular comorbidities, in addition to generating complex clinical conditions. This has forced the scientific community to explore different strategies that allow combating this viral infection as well as treating life-threatening systemic effect of the infection on the individual. In this work, we have reviewed the most recent scientific evidence to provide a comprehensive panorama regarding the biotechnological strategies that have been proposed to combat this new viral infection. We have focused our analysis on vaccine production, nanotechnology applications, repurposing of know drugs for unrelated pathologies, and the search for bioactive molecules obtained from natural products. The goals include safely use as potential prophylactic or therapeutic treatments, based on in silico and in vivo studies, including clinical trials around the world for the correct and timely diagnosis of the infection. This review aims to highlight the development of new ideas that can decrease the time lines for research output and improve research quality while at the same time, keeping in mind the efficacy and safety aspects of these potential biotechnological strategies.

Indexed as

AntiviralsCOVID-19Drugs and COVID-19Nanothenology against COVID-19Natural products against COVID-19Vaccines against COVID-19

Identifiers

PMID33457170
PMCPMC7796695

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.