Evidence map›Paper›PMID 33457075›Full record

ArticleOncoimmunology2020

Anti-NKG2D single domain-based antibodies for the modulation of anti-tumor immune response.

Adeline Raynaud, Klervi Desrumeaux, Laurent Vidard, Elise Termine, Daniel Baty, Patrick Chames, Emmanuelle Vigne, Brigitte Kerfelec

Open access · goldAbstract read
In one paragraph

Article in Oncoimmunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 39 citations in OpenAlex.

  1. IL-15/NKG2D signaling-mediated activation of CD8Journal of thoracic disease · 2026
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  10. NKG2D-bispecific enhances NK and CD8+ T cell antitumor immunity.Cancer immunology, immunotherapy : CII · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Adeline RaynaudCancer Research Center of Marseille, INSERM, CNRS, Aix Marseille Université, Institut Paoli - Calmettes, Marseille, France.
Klervi DesrumeauxSanofi Oncology, Vitry-sur-Seine, France.
Laurent VidardSanofi Oncology, Vitry-sur-Seine, France.
Elise TermineCancer Research Center of Marseille, INSERM, CNRS, Aix Marseille Université, Institut Paoli - Calmettes, Marseille, France.
Daniel BatyCancer Research Center of Marseille, INSERM, CNRS, Aix Marseille Université, Institut Paoli - Calmettes, Marseille, France.
Patrick ChamesCancer Research Center of Marseille, INSERM, CNRS, Aix Marseille Université, Institut Paoli - Calmettes, Marseille, France.
Emmanuelle VigneSanofi Oncology, Vitry-sur-Seine, France.
Brigitte KerfelecCancer Research Center of Marseille, INSERM, CNRS, Aix Marseille Université, Institut Paoli - Calmettes, Marseille, France.ORCID 0000-0001-8423-3423
Centre National de la Recherche Scientifique · FRSanofi (France) · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The natural killer group 2 member D (NKG2D) receptor is a C-type lectin-like activating receptor mainly expressed by cytotoxic immune cells including NK, CD8

Indexed as

NeoplasmsSingle-Domain AntibodiesHumansImmunityKiller Cells, NaturalNK Cell Lectin-Like Receptor Subfamily KTumor MicroenvironmentNK Cell Lectin-Like Receptor Subfamily KSingle-Domain Antibodiescell engagersHER2NK cellsNKG2D/NKG2DL axissingle-domain antibody

Identifiers

PMID33457075
PMCPMC7781768
OpenAlexW3116321166

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.