Evidence map›Paper›PMID 33457029›Full record

ArticleCase reports in ophthalmological medicine2020

Recurrent Herpes Zoster Ophthalmicus Preceded by Anabolic Steroids and High-Dose L-Arginine.

Stephen A LoBue, Adam Goldman, Richard A Giovane, Stacy M Carlson, Michael Bivona, Sinan Albear, Thomas D LoBue

Open access · goldAbstract readCase Reports
In one paragraph

Article in Case reports in ophthalmological medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Stephen A LoBueDepartment of Ophthalmology, SUNY Downstate, Brooklyn, NY 11203, USA.ORCID https://orcid.org/0000-0003-2899-7730
Adam GoldmanDepartment of Ophthalmology, SUNY Downstate, Brooklyn, NY 11203, USA.ORCID https://orcid.org/0000-0002-7611-1124
Richard A GiovaneLV Stabler Hospital, Greenville, AL 36037, USA.ORCID https://orcid.org/0000-0002-8547-2693
Stacy M CarlsonMontefiore Medical Center, Bronx, NY 10467, USA.ORCID https://orcid.org/0000-0001-6928-7984
Michael BivonaDepartment of Ophthalmology, SUNY Downstate, Brooklyn, NY 11203, USA.ORCID https://orcid.org/0000-0002-7189-4115
Sinan AlbearDepartment of Ophthalmology, SUNY Downstate, Brooklyn, NY 11203, USA.
Thomas D LoBueLoBue Laser & Eye Medical Centers, Murrieta, CA 92562, USA.ORCID https://orcid.org/0000-0002-3963-5391
SUNY Downstate Health Sciences University · USMontefiore Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo report a case of a 34-year-old male with recurrent herpes zoster ophthalmicus (HZO) preceded by a 6-week cycle of anabolic steroids and high-dose amino acid supplementation.

conclusionIn vitro L-arginine supplementation has been associated with the proliferation and virulence of a variety of herpes viruses. Anabolic steroids have also been demonstrated by various studies to negatively affect cell-mediated immunity necessary to prevent viral infection. Thus, it is possible that anabolic steroids in conjunction with increased L-arginine intake may have precipitated a recurrent HZO in a previously healthy, immunocompetent individual.

Identifiers

PMID33457029
PMCPMC7785356
OpenAlexW3115504685

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.