ReviewCraniomaxillofacial trauma & reconstruction2020
Etiopathogenesis of Trismus in Patients With Head and Neck Cancer: An Exploratory Literature Review.
Review in Craniomaxillofacial trauma & reconstruction, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
14 citing papers in PubMed.
- Jaw exercise in head and neck cancer patients for prevention of temporomandibular disorders: a randomized controlled trial.Journal of cancer survivorship : research and practice · 2026Trial
- Endodontic Management Before, During and After Head and Neck Radiotherapy: Biological, Diagnostic and Clinical Considerations in Head and Neck Cancer Patients.International endodontic journal · 2026Review
- Imaging findings in the temporomandibular joint complex following radiation therapy for head and neck cancer: a review.Insights into imaging · 2026Review
- Symptom Clusters and Related Factors of Late Toxicities in Head and Neck Cancer Survivors After Radiation Therapy: A Cross-Sectional Study.Nursing reports (Pavia, Italy) · 2026Article
- A higher number of chemotherapy cycles given during and after radiation is linked to increased rates of radiation-induced trismus in locally advanced nasopharyngeal cancer patients.Discover oncology · 2025Article
- Severe and Long-Term Side Effects of Radiotherapy for Nasopharyngeal Cancer: A Case Report.Cureus · 2025Article
- Global Immune-Nutrition-Inflammation Index as a novel comprehensive biomarker in predicting the radiation-induced trismus rates in locally advanced nasopharyngeal carcinoma patients.Biomolecules & biomedicine · 2024Review
- Treatment Complications of Head and Neck Cancers and Rehabilitation Measures: A Narrative Review.Cureus · 2024Review
- Review
- Boswellia serrata Enhances Passive Range-of-Motion Exercises in Radiation-Induced Trismus: A Case Report.Cureus · 2024Article
- Lymphedema and Trismus after Head and Neck Cancer, and the Impact on Body Image and Quality of Life.Cancers · 2024Article
- Article
- Advances and Controversies in the Management of Osteoradionecrosis After Head and Neck Cancer Treatment: A Narrative Review.Journal of maxillofacial and oral surgery · 2022Review
- VMAT with CCC Algorithm Optimizes Trismus Prevention: Dose-Response Analysis of Jaw Muscles Dmean and Dmax in T3-T4 Nasopharyngeal Carcinoma.Technology in cancer research & treatmentArticle
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Trismus refers to a person's inability to normally open his or her mouth. Trismus can occur as a symptom due to tumor ingrowth or it can occur postsurgical following the treatment for head and neck cancer. Radiation-induced trismus is also a relatively common oral complication. This review aimed at reviewing the etiopathogenesis of trismus in patients with head and neck cancer. Of the 16 publications included after final screening, of which one was a nonrandomized control trial, one a randomized control trial, 6 prospective cohort studies, and 8 retrospective cohort studies. Among them, 6 articles addressed the possible mechanism for trismus related to tumor ingrowth, 8 articles suggested the likely reason for trismus in patients who had undergone radiation therapy and 2 articles addressed the postsurgical cause for trismus. This review highlights the possible involvement of infratemporal fossa as a predetermining factor for developing trismus related to tumor extension. The molecular mechanism of radiation-induced fibrosis is well studied in the literature.
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