Evidence map›Paper›PMID 33456676›Full record

ArticleOxidative medicine and cellular longevity2020

Hyaluronic Acid Improves Hydrogen Peroxide Modulatory Effects on Calcium Channel and Sodium-Potassium Pump in 4T1 Breast Cancer Cell Line.

Ardeshir Abbasi, Nafiseh Pakravan, Zuhair Mohammad Hassan

Open access · hybridAbstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Preparation and Investigation ofPharmaceuticals (Basel, Switzerland) · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Ardeshir AbbasiDepartment of Immunology, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran.ORCID https://orcid.org/0000-0002-3649-6146
Nafiseh PakravanDepartment of Immunology, Medical School, Alborz University of Medical Sciences, Karaj, Iran.ORCID https://orcid.org/0000-0002-9355-1738
Zuhair Mohammad HassanDepartment of Immunology, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran.ORCID https://orcid.org/0000-0001-9197-1416
Tarbiat Modares University · IRJahrom University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Maintaining homeostasis of ion concentrations is critical in cancer cells. Under hypoxia, the levels of channels and pumps in cancer cells are more active than normal cells suggesting ion channels as a suitable therapeutic target. One of the contemporary ways for cancer therapy is oxidative stress. However, the effective concentration of oxidative stress on tumor cells has been reported to be toxic for normal cells as well. In this study, we benefited from the modifying effects of hyaluronic acid (HA) on H

Indexed as

AnimalsB7-H1 AntigenBiomarkers, TumorBiphenyl CompoundsBreast NeoplasmsCalciumCalcium ChannelsCell HypoxiaCell Line, TumorFemaleHyaluronic AcidHydrogen PeroxideMicePicratesPotassiumSodium1,1-diphenyl-2-picrylhydrazylB7-H1 AntigenBiomarkers, TumorBiphenyl CompoundsCalciumCalcium ChannelsHyaluronic AcidHydrogen PeroxidePicratesPotassiumSodiumSodium-Potassium-Exchanging ATPase

Identifiers

PMID33456676
PMCPMC7787766
OpenAlexW3117730154

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.