Evidence map›Paper›PMID 33456674›Full record

ArticleOxidative medicine and cellular longevity2020

The Effects of Hypoxia-Reoxygenation in Mouse Digital Flexor Tendon-Derived Cells.

Chen Chen, Wei Feng Mao, Ya Fang Wu

Open access · hybridAbstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. ATP purinergic receptor signalling promotes Sca-1Cell communication and signaling : CCS · 2023
    Article
  3. Deletion of theInternational journal of molecular sciences · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Chen ChenDepartment of Hand Surgery, Affiliated Hospital of Nantong University, Nantong, Jiangsu, China.ORCID https://orcid.org/0000-0003-2008-7580
Wei Feng MaoDepartment of Hand Surgery, Affiliated Hospital of Nantong University, Nantong, Jiangsu, China.ORCID https://orcid.org/0000-0002-3094-0293
Ya Fang WuDepartment of Hand Surgery, Affiliated Hospital of Nantong University, Nantong, Jiangsu, China.ORCID https://orcid.org/0000-0002-9582-252X
Nantong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveIschemia-reperfusion injury refers to the exacerbated and irreversible tissue damage caused by blood flow restoration after a period of ischemia. The hypoxia-reoxygenation (H/R) model in vitro is ideal for studying ischemia-reperfusion injury at the cellular level. We employed this model and investigated the effects of cobalt chloride- (CoCl MATERIALS AND

methodsVarious H/R conditions were simulated via treatment of tendon-derived cells with different concentrations of CoCl

resultsThe cells treated with low concentrations of CoCl

conclusionsTendon-derived cells were highly tolerant to the hypoxic environments induced by CoCl

Indexed as

AnimalsApoptosisbcl-2-Associated X ProteinCell HypoxiaCell ProliferationCell ShapeCell SurvivalCobaltCollagenFemaleGene Expression RegulationHypoxia-Inducible Factor 1, alpha SubunitMalondialdehydeMice, Inbred C57BLMitochondriaOxidative Stressbcl-2-Associated X ProteinCobaltcobaltous chlorideCollagenHypoxia-Inducible Factor 1, alpha SubunitMalondialdehydeOxygenRNA, MessengerVascular Endothelial Growth Factor A

Identifiers

PMID33456674
PMCPMC7787768
OpenAlexW3110846308

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.