Evidence map›Paper›PMID 33456641›Full record

ArticleThe annals of applied statistics2020

BAYESIAN VARIABLE SELECTION FOR SURVIVAL DATA USING INVERSE MOMENT PRIORS.

Amir Nikooienejad, Wenyi Wang, Valen E Johnson

Abstract read
In one paragraph

Article in The annals of applied statistics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Amir NikooienejadTexas A&M University.
Wenyi WangMD Anderson Cancer Center.
Valen E JohnsonTexas A&M University.

Funding

Tumor Evolution and Metastasis ProgramP30CA016672 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Scott Kopetz · 1985 to 2026
$290.8M
Consistent variable selection in p>>n settingsR01CA158113 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI JOHNSON, VALEN EARL · 2011 to 2020
$2.8M
Statistical methods for genomic analysis of heterogeneous tumorsR01CA183793 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI WANG, WENYI · 2014 to 2018
$1.7M
Bioinformatics Tools for Genomic Analysis of Tumor and Stromal Pathways in CancerR01CA174206 · NCI · DANA-FARBER CANCER INST · PI PARMIGIANI, GIOVANNI LUIGI · 2013 to 2017
$1.7M
NCI NIH HHS P30 CA016672NCI NIH HHS R01 CA158113NCI NIH HHS R01 CA174206NCI NIH HHS R01 CA183793
6 · The paper itself

Abstract

Efficient variable selection in high dimensional cancer genomic studies is critical for discovering genes associated with specific cancer types and for predicting response to treatment. Censored survival data is prevalent in such studies. In this article we introduce a Bayesian variable selection procedure that uses a mixture prior composed of a point mass at zero and an inverse moment prior in conjunction with the partial likelihood defined by the Cox proportional hazard model. The procedure is implemented in the R package BVSNLP, which supports parallel computing and uses a stochastic search method to explore the model space. Bayesian model averaging is used for prediction. The proposed algorithm provides better performance than other variable selection procedures in simulation studies, and appears to provide more consistent variable selection when applied to actual genomic datasets.

Indexed as

Bayesian Variable SelectionCancer GenomicsCox Proportional Hazard ModelHigh Dimensional DataNonlocal PriorSurvival Data Analysis

Identifiers

PMID33456641
PMCPMC7808442

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.