Evidence map›Paper›PMID 33456640›Full record

ArticleBiomicrofluidics2021

Acoustofluidic phase microscopy in a tilted segmentation-free configuration.

Julián Mejía Morales, Björn Hammarström, Gian Luca Lippi, Massimo Vassalli, Peter Glynne-Jones

Abstract read
In one paragraph

Article in Biomicrofluidics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Meet the editor series-Massimo Vassalli.Biophysical reviews · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Julián Mejía MoralesORCID 0000-0001-6494-8624
Björn HammarströmORCID 0000-0002-3422-1325
Gian Luca LippiInstitut de Physique de Nice, Université Côte d'Azur, CNRS, 06560 Valbonne, France.ORCID 0000-0002-9545-240X
Massimo VassalliJames Watt School of Engineering, University of Glasgow, G12 8LT Glasgow, United Kingdom.ORCID 0000-0002-3063-4376
Peter Glynne-JonesEngineering Sciences, University of Southampton, SO17 1BJ Southampton, United Kingdom.ORCID 0000-0001-5684-3953

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A low-cost device for registration-free quantitative phase microscopy (QPM) based on the transport of intensity equation of cells in continuous flow is presented. The method uses acoustic focusing to align cells into a single plane where all cells move at a constant speed. The acoustic focusing plane is tilted with respect to the microscope's focal plane in order to obtain cell images at multiple focal positions. As the cells are displaced at constant speed, phase maps can be generated without the need to segment and register individual objects. The proposed inclined geometry allows for the acquisition of a vertical stack without the need for any moving part, and it enables a cost-effective and robust implementation of QPM. The suitability of the solution for biological imaging is tested on blood samples, demonstrating the ability to recover the phase map of single red blood cells flowing through the microchip.

Identifiers

PMID33456640
PMCPMC7787693

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.