Evidence map›Paper›PMID 33456595›Full record

ArticleJournal of medicine and life

Transgenerational Effects of Traumatic Historical Events on the Incidence of Metabolic Syndrome/ Nonalcoholic Fatty Liver Disease in the Romanian Population.

Victor Stoica, Daniel Adrian Gardan, Ileana Constantinescu, Iuliana Petronela Gardan, Bogdan Calenic, Mircea Diculescu

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Article in Journal of medicine and life. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Victor StoicaDepartment of Gastroenterology, "Carol Davila" University of Medicine and Pharmacy", Bucharest, Romania.
Daniel Adrian GardanFaculty of Economic Sciences, Spiru Haret University, Bucharest, Romania.
Ileana ConstantinescuDepartment of Immunology and Transplant Immunology, "Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania.
Iuliana Petronela GardanFaculty of Economic Sciences, Spiru Haret University, Bucharest, Romania.
Bogdan CalenicDepartment of Biochemistry, Faculty of Dentistry, "Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania.
Mircea DiculescuDepartment of Gastroenterology, "Carol Davila" University of Medicine and Pharmacy", Bucharest, Romania.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Concerns for successful public health management are integrated into the core business of government-responsible institutions. Diseases associated with metabolic syndrome are very common in the Romanian population. In our study, we focused on the cardiovascular and non-alcoholic fatty liver disease (NAFLD). The article starts from the hypothesis that the increased incidence of such diseases is determined today by the cumulative effect of traumatic historical events such as the famine of 1946-47 and the communist political regime specific to the 80s and 90s. This study aims to present the arguments that indicate the correlation of economic variables whose variation can be easily determined by traumatic events that affected the economy, with variables able to measure the incidence of various diseases usually associated with metabolic syndrome or NAFLD. A series of statistical data were analyzed from the official sources available in the form of consecutive value data for the 1995-2018 period. The results highlighted a direct and strong link between the variable gross domestic product (GDP) per capita in USD, 2011 purchasing power parity (PPP) and specific incidence of circulatory, nutritional endocrine and metabolic diseases, as well as a strong and inverse link between GDP and infant's deaths per 1000 live births. Conclusions highlight that the effects of traumatic historical events must be made aware through medical education of the population, supporting the idea according to which the incidence of various metabolic diseases is greater for the offspring of those who have actively suffered during such events.

Indexed as

Analysis of VarianceFeeding BehaviorGross Domestic ProductHumansIncidenceInfantInfant MortalityMetabolic SyndromeNon-alcoholic Fatty Liver DiseaseRegression AnalysisRisk FactorsRomaniaWounds and InjurieslifestyleMetabolic diseasetransgenerational epigenetic inheritancetraumatic event

Identifiers

PMID33456595
PMCPMC7803300

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.