Evidence map›Paper›PMID 33456524›Full record

ArticleExperimental and therapeutic medicine2021

DUOX2 participates in skin aging induced by UVB in HSF2 cells by activating NF-κB signaling.

Xiaoqing Xiao, Minghuan Huang, Chunyan Fan, Fuguo Zuo

Abstract read
In one paragraph

Article in Experimental and therapeutic medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Heat-KilledAntioxidants (Basel, Switzerland) · 2022
    Article
  4. Article
  5. Article
  6. Article
  7. Topical Administration of 15-Deoxy-Mediators of inflammation · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Xiaoqing XiaoDepartment of Dermatology, Shanghai East Hospital, Tongji University School of Medicine, Shanghai 200120, P.R. China.
Minghuan HuangDepartment of Dermatology, Shanghai East Hospital, Tongji University School of Medicine, Shanghai 200120, P.R. China.
Chunyan FanDepartment of Dermatology, Shanghai East Hospital, Tongji University School of Medicine, Shanghai 200120, P.R. China.
Fuguo ZuoDepartment of Dermatology, Shanghai East Hospital, Tongji University School of Medicine, Shanghai 200120, P.R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Skin and in particular photoaging or premature aging, are caused by a variety of factors, including hormone imbalance and exposure to ultraviolet radiation. The aim of the present study was to explore the roles of Dual oxidase 2 (DUOX2) and related NF-κB signals in skin photoaging. Cell models of photoaging were constructed by irradiating human skin fibroblast lines (HSF2) with ultraviolet B (UVB) of different doses (0, 15, 30 and 60 mj/cm

Indexed as

DUOX2inflammatory responseNF-κBphotoagingROS

Identifiers

PMID33456524
PMCPMC7792488

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.