Evidence map›Paper›PMID 33456470›Full record

ArticleInternational journal of analytical chemistry2020

Establishment and Validation of a Liquid Chromatography-Tandem Mass Spectrometry Method for the Determination of Tigecycline in Critically Ill Patients.

Fen Yao, Yifan Wang, Yating Hou, Xipei Wang, Jinhua Lan, Zheng Wu, Yirong Wang, Chunbo Chen

Abstract read
In one paragraph

Article in International journal of analytical chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Observational
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Fen YaoSchool of Biology and Biological Engineering, South China University of Technology, Guangzhou 510006, Guangdong, China.
Yifan WangSchool of Biology and Biological Engineering, South China University of Technology, Guangzhou 510006, Guangdong, China.
Yating HouDepartment of Emergency Medicine, Maoming People's Hospital, 101 Weimin Road, Maoming 525000, Guangdong, China.ORCID https://orcid.org/0000-0001-5684-2475
Xipei WangDepartment of Medical Sciences, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangdong Cardiovascular Institute, 106 Zhongshan Er Road, Guangzhou 510080, China.
Jinhua LanDepartment of Critical Care Medicine, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, 106 Zhongshan Er Road, Guangzhou 510080, Guangdong, China.
Zheng WuDepartment of Critical Care Medicine, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, 106 Zhongshan Er Road, Guangzhou 510080, Guangdong, China.
Yirong WangDepartment of Critical Care Medicine, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, 106 Zhongshan Er Road, Guangzhou 510080, Guangdong, China.
Chunbo ChenSchool of Biology and Biological Engineering, South China University of Technology, Guangzhou 510006, Guangdong, China.ORCID https://orcid.org/0000-0001-5662-497X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Utilizing tigecycline-d9 as an internal standard (IS), we establish and validate a simple, effective, and rapid liquid chromatography-tandem mass spectrometry (LC-MS/MS) method for the quantitative measurement of tigecycline (TGC) in patient plasma. Acetonitrile was used as a precipitant to process plasma samples by a protein precipitation method. The analyte and IS were separated on an HSS T3 (2.1 × 100 mm, 3.5

Identifiers

PMID33456470
PMCPMC7785388

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.