ReviewTobacco induced diseases2021
The effect of e-cigarettes on smoking cessation and cigarette smoking initiation: An evidence-based rapid review and meta-analysis.
Review in Tobacco induced diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 7 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
33 citing papers in PubMed, 7 syntheses or guidelines pooled it.
- Electronic cigarettes and subsequent cigarette smoking in young people: A systematic review.Addiction (Abingdon, England) · 2025Pooled it
- Electronic cigarettes for smoking cessation.The Cochrane database of systematic reviews · 2025Pooled it
- Association of electronic cigarette use and suicidal behaviors: a systematic review and meta-analysis.BMC psychiatry · 2024Pooled it
- Electronic cigarettes for smoking cessation.The Cochrane database of systematic reviews · 2024Pooled it
- Electronic cigarettes for smoking cessation.The Cochrane database of systematic reviews · 2022Pooled it
- Electronic cigarettes for smoking cessation.The Cochrane database of systematic reviews · 2021Pooled it
- Electronic cigarettes for smoking cessation.The Cochrane database of systematic reviews · 2021Pooled it
- Effects of Moral Frames Within Vaping Prevention Messages on Current smokers' Support for Electronic Cigarette Regulations.Journal of health communication · 2023Trial
- Prevalence, predictors and burden of secondhand tobacco smoke (SHS) exposure in Saudi Arabia: a large-scale cross-sectional survey.BMJ open · 2026Article
- Healthcare professionals' roles, perceptions, and interventions relating to e-cigarette and vaping practices: a scoping review.BMC public health · 2026Article
- Attitudes of people diagnosed with cancer and cancer care providers towards use of nicotine vaping products in high-income countries: a scoping review.Journal of cancer survivorship : research and practice · 2025Article
- Knowledge, attitude, practice and policy support of college students toward electronic cigarette use: a nationwide multicentric study in Iran.BMC public health · 2025Article
- Assessment of the prevalence, knowledge, and perceptions of e-cigarette use among the Palestinian community: a cross-sectional study.Scientific reports · 2025Article
- Building consensus on a set of ENDS-specific pictorial health warnings: a Delphi study among a tobacco control expert panel.Tobacco control · 2025Article
- Knowledge and awareness of the health effects of electronic cigarette among college students.Journal of medicine and life · 2025Article
- Perspectives of Sexual and Gender Minority Youth on Anti-Vaping Messages in Social Media.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2025Article
- Assessing the knowledge, attitude and practice of electronic cigarettes and their associated factors among undergraduate students of Institute of Medicine, Nepal: a cross-sectional study.BMC public health · 2024Article
- Current perspective on e-cigarette use and respiratory outcomes: mechanisms and messaging.Expert review of respiratory medicine · 2024Review
- What are the characteristics of disposable electronic cigarettes users in Switzerland? A quantitative study among 14-25 year olds.BMJ public health · 2024Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionThe contribution made by e-cigarettes to smoking cessation continues to be controversial. Reports suggest that teenagers are becoming increasingly addicted to e-cigarettes and that e-cigarette use in adolescents is associated with subsequent cigarette smoking.
methodsSystematic searches of eleven databases were conducted (January 2015 to June 2020). Systematic reviews, randomized controlled trials (RCTs) and cohort studies comparing e-cigarettes with placebo e-cigarettes, nicotine replacement therapy (NRT) or no e-cigarette use were included. The two primary outcomes were smoking cessation among smokers and smoking initiation among non-smoking teenagers. The secondary outcome was adverse events. Data were synthesized using risk ratio (RR) or adjusted odds ratio (AOR) with 95% confidence interval (CI).
resultsSix systematic reviews, 5 RCTs and 24 cohort studies were identified. For smoking cessation, findings from 4 systematic reviews indicated that e-cigarettes contributed to cessation while one found the opposite. Meta-analysis of 5 RCTs suggested that e-cigarettes were superior to NRT or placebo for smoking cessation (RR=1.55; 95% CI: 1.00-2.40; I
conclusionsLow certainty evidence suggests that e-cigarettes appear to be potentially effective for smoking cessation. The use of e-cigarettes in adolescents may be associated with smoking initiation. No serious adverse events were reported.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.