ArticleDose-response : a publication of International Hormesis Society
Whole Body Low Dose Computed Tomography Using Third-Generation Dual-Source Multidetector With Spectral Shaping: Protocol Optimization and Literature Review.
Article in Dose-response : a publication of International Hormesis Society. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- Prospective Multireader Evaluation of Photon-counting CT for Multiple Myeloma Screening.Radiology. Imaging cancer · 2022Trial
- Hip Reconstruction in Children with Cerebral Palsy: Comparing Treatment Plans Derived from Pelvic Radiographs Versus Those from Hip CTs.Journal of clinical medicine · 2026Article
- Dose optimization for CT scans of the temporal bone using spectral shaping tin filter.Journal of applied clinical medical physics · 2026Article
- Automated Measurement of Effective Radiation Dose byTomography (Ann Arbor, Mich.) · 2024Article
- Enhanced architecture and implementation of spectrum shaping codes.PeerJ. Computer science · 2024Article
- Potential of Unenhanced Ultra-Low-Dose Abdominal Photon-Counting CT with Tin Filtration: A Cadaveric Study.Diagnostics (Basel, Switzerland) · 2023Article
- The utility ofReports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology · 2022Article
- Whole-body magnetic resonance imaging (WBMRI) versus whole-body computed tomography (WBCT) for myeloma imaging and staging.Skeletal radiology · 2022Review
- Whole Body Low Dose Computed Tomography (WBLDCT) Can Be Comparable to Whole-Body Magnetic Resonance Imaging (WBMRI) in the Assessment of Multiple Myeloma.Diagnostics (Basel, Switzerland) · 2021Article
- Ultra-Low-Dose Whole-Body Computed Tomography Protocol Optimization for Patients With Plasma Cell Disorders: Diagnostic Accuracy and Effective Dose Analysis From a Reference Center.Frontiers in oncology · 2021Article
- Evaluation of AI-Based Segmentation Tools for COVID-19 Lung Lesions on Conventional and Ultra-low Dose CT Scans.Dose-response : a publication of International Hormesis SocietyArticle
- Rhinoplasty Pre-Surgery Models by Using Low-Dose Computed Tomography, Magnetic Resonance Imaging, and 3D Printing.Dose-response : a publication of International Hormesis SocietyArticle
- Investigating Dual-Energy CT Post-Contrast Phases for Liver Iron Quantification: A Preliminary Study.Dose-response : a publication of International Hormesis SocietyArticle
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
For decades, the main imaging tool for multiple myeloma (MM) patient's management has been the conventional skeleton survey. In 2014 international myeloma working group defined the advantages of the whole-body low dose computed tomography (WBLDCT) as a gold standard, among imaging modalities, for bone disease assessment and subsequently implemented this technique in the MM diagnostic workflow. The aim of this study is to investigate, in a group of 30 patients with a new diagnosis of MM, the radiation dose (CT dose index, dose-length product, effective dose), the subjective image quality score and osseous/extra-osseous findings rate with a modified WBLDCT protocol. Spectral shaping and third-generation dual-source multidetector CT scanner was used for the assessment of osteolytic lesions due to MM, and the dose exposure was compared with the literature findings reported until 2020. Mean radiation dose parameters were reported as follows: CT dose index 0.3 ± 0.1 mGy, Dose-Length Product 52.0 ± 22.5 mGy*cm, effective dose 0.44 ± 0.19 mSv. Subjective image quality was good/excellent in all subjects. 11/30 patients showed osteolytic lesions, with a percentage of extra-osseous findings detected in 9/30 patients. Our data confirmed the advantages of WBLDCT in the diagnosis of patients with MM, reporting an effective dose for our protocol as the lowest among previous literature findings.
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