Evidence map›Paper›PMID 33456195›Full record

ArticleProceedings (Baylor University. Medical Center)2020

Statin-induced necrotizing autoimmune myopathy.

Syed A Huda, Sanjay Yadava, Sara Kahlown, Muhammad S Farooqi, Stephanie Bryant, Ronald Russo

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Proceedings (Baylor University. Medical Center), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Syed A HudaDepartment of Internal Medicine, State University of New York Upstate Medical University, Syracuse, New York.ORCID https://orcid.org/0000-0002-2605-8273
Sanjay YadavaDepartment of Internal Medicine, State University of New York Upstate Medical University, Syracuse, New York.ORCID https://orcid.org/0000-0003-0097-8802
Sara KahlownDepartment of Internal Medicine, UHS Wilson Medical Center, Johnson City, New York.
Muhammad S FarooqiDepartment of Internal Medicine, Mayo Hospital, Lahore, Pakistan.
Stephanie BryantDepartment of Pathology, State University of New York Upstate Medical University, Syracuse, New York.
Ronald RussoDepartment of Internal Medicine, State University of New York Upstate Medical University, Syracuse, New York.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Statins are the most widely used class of drug in the United States. They lower blood cholesterol levels by inhibiting 3-hydroxy-3-methyl-glutaryl-coenzyme A reductase. Common side effects include myalgias and a mild increase in liver function tests. Statin-induced necrotizing autoimmune myopathy (SINAM) is a very rare side effect that is independent of the type and duration of statin use. Treatment involves high-dose steroids and immunosuppressants such as azathioprine, methotrexate, or mycophenolate mofetil. Nonresponders and patients with severe weakness can be treated with intravenous immunoglobulin or rituximab. We present a case of SINAM that was successfully treated with intravenous immunoglobulin.

Indexed as

ImmunosuppressantsrhabdomyolysisSINAMstatin-induced necrotizing autoimmune myopathystatins

Identifiers

PMID33456195
PMCPMC7785182

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.