ArticleInternal medicine (Tokyo, Japan)2021
Treatment with a Direct Oral Anticoagulant for Nonbacterial Thrombotic Endocarditis.
Article in Internal medicine (Tokyo, Japan), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed, 2 syntheses or guidelines pooled it, 11 citations in OpenAlex.
- Cancer-associated Marantic Endocarditis and Direct Oral Anticoagulants: Case Report and Systematic Review.Current cardiology reviews · 2026Pooled it
- Non-bacterial Thrombotic Endocarditis in Lung Cancer: A Systematic Review.Current cardiology reviews · 2025Pooled it
- Acute ischemic stroke, active malignancy and non-bacterial thrombotic endocarditis: an exploratory prospective observational study.Scientific reports · 2026Observational
- Clinical insights into nonbacterial thrombotic endocarditis in cancer patients: A case-based systematic review.ARYA atherosclerosis · 2025Review
- Cardiac Masses Discovered by Echocardiogram; What to Do Next?Structural heart : the journal of the Heart Team · 2023Review
- Review
- Case report: New is not always better: treatment of non-bacterial thrombotic endocarditis.Frontiers in cardiovascular medicine · 2023Article
- A rare case of metastatic pancreatic adenocarcinoma presenting as a pulmonary embolism from nonbacterial thrombotic endocarditis.Radiology case reports · 2022Article
- Reversibility of valve regurgitation due to cancer-related non-bacterial thrombotic endocarditis after switching direct oral anticoagulation for heparin.BMJ case reports · 2022Article
- Endocarditis Caused by Zoonotic Pathogens and Antiphospholipid Syndrome Are Possible Differential Diagnoses.Internal medicine (Tokyo, Japan) · 2021Article
- Endocarditis Caused by Zoonotic Pathogens and Antiphospholipid Syndrome Are Possible Differential Diagnoses: Authors' Reply.Internal medicine (Tokyo, Japan) · 2021Article
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We herein report a case of nonbacterial thrombotic endocarditis (NBTE) in a patient with previously undiagnosed lung cancer. A 62-year-old woman presented to our hospital with multiple cerebral infarctions. There was no evidence of valvular heart disease or vegetations. Whole-leg ultrasonography revealed deep vein thrombosis of the left peroneal vein. We administered direct oral anticoagulants (DOACs) for a presumed diagnosis of paradoxical embolisms caused by patent foramen ovale. Unfortunately, she experienced further embolization and died. At a postmortem examination, she was diagnosed with NBTE and metastatic adenocarcinoma of the lung. Our experience with this patient suggests that DOACs may be an insufficient treatment for NBTE.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.