Evidence map›Paper›PMID 33456034›Full record

ArticleInternal medicine (Tokyo, Japan)2021

Glomerulonephritis Caused by Bartonella spp. Infective Endocarditis: The Difficulty and Importance of Differentiation from Anti-neutrophil Cytoplasmic Antibody-related Rapidly Progressive Glomerulonephritis.

Ayumi Yoshifuji, Yuuka Hibino, Motoaki Komatsu, Seiichi Yasuda, Koji Hosoya, Emi Kobayashi, Yuko Baba, Shigemichi Hirose, Akinori Hashiguchi, Yoshihiko Kanno and 1 more

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. ASM case reports · 2025
    Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. A case ofIDCases · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Ayumi YoshifujiDivision of Nephrology, Department of Internal Medicine, Tokyo Saiseikai Central Hospital, Japan.
Yuuka HibinoDivision of Nephrology, Department of Internal Medicine, Tokyo Saiseikai Central Hospital, Japan.
Motoaki KomatsuDivision of Nephrology, Department of Internal Medicine, Tokyo Saiseikai Central Hospital, Japan.
Seiichi YasudaDivision of Nephrology, Department of Internal Medicine, Tokyo Saiseikai Central Hospital, Japan.
Koji HosoyaDivision of Nephrology, Department of Internal Medicine, Tokyo Saiseikai Central Hospital, Japan.
Emi KobayashiDivision of Nephrology, Department of Internal Medicine, Tokyo Saiseikai Central Hospital, Japan.
Yuko BabaDepartment of Dermatology, Tokyo Saiseikai Central Hospital, Japan.
Shigemichi HiroseDepartment of Pathology, Tokyo Saiseikai Central Hospital, Japan.
Akinori HashiguchiDepartment of Pathology, Keio University School of Medicine, Japan.
Yoshihiko KannoDepartment of Nephrology, Tokyo Medical University, Japan.
Munekazu RyuzakiDivision of Nephrology, Department of Internal Medicine, Tokyo Saiseikai Central Hospital, Japan.
Saiseikai Central Hospital · JPKeio University · JPTokyo Medical University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 65-year-old man with valvular disorder presented to his physician because of widespread purpura in both lower extremities. Blood tests showed elevated serum creatinine levels and proteinase 3-anti-neutrophil cytoplasmic antibody (ANCA) with hematuria, suggesting ANCA-related rapidly progressive glomerulonephritis (RPGN). Although multiple blood cultures were negative, transthoracic echocardiography revealed warts in the valves, and a renal biopsy also showed findings of glomerular infiltration by mononuclear leukocytes and C3 deposition in the glomeruli, suggesting infection-related glomerulonephritis. Later, Bartonella antibody turned positive. Antimicrobial treatment improved the purpura and renal function without any recurrence. ANCA-positive RPGN requires the exclusion of infective endocarditis, especially that induced by Bartonella spp.

Indexed as

BartonellaEndocarditisEndocarditis, BacterialGlomerulonephritisAgedAntibodies, Antineutrophil CytoplasmicHumansMaleAntibodies, Antineutrophil CytoplasmicANCABartonellainfective endocarditisrapidly progressive glomerulonephritis

Identifiers

PMID33456034
PMCPMC8263179
OpenAlexW3123211339

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.