Evidence map›Paper›PMID 33455428›Full record

ArticleJournal of the American Heart Association2021

Ablation of Atrial Fibrillation in Patients With Hypertrophic Cardiomyopathy: Treatment Strategy, Characteristics of Consecutive Atrial Tachycardia and Long-Term Outcome.

Leon Dinshaw, Paula Münkler, Benjamin Schäffer, Niklas Klatt, Christiane Jungen, Jannis Dickow, Annika Tamenang, Ruben Schleberger, Simon Pecha, Hans Pinnschmidt and 4 more

Open access · goldAbstract read
In one paragraph

Article in Journal of the American Heart Association, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
5.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 40 citations in OpenAlex.

  1. Atrial electrophysiology in hypertrophic cardiomyopathy: current insights and knowledge gaps.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2026
    Review
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  7. Impact of catheter ablation on atrial fibrillation outcomes in various cardiomyopathies: findings from LGE-MRI quantified atrial fibrosis analysis.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2025
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  14. 2024 European Heart Rhythm Association/Heart Rhythm Society/Asia Pacific Heart Rhythm Society/Latin American Heart Rhythm Society expert consensus statement on catheter and surgical ablation of atrial fibrillation.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2024
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 1 country.

Leon DinshawDepartment of Cardiology University Heart and Vascular Center HamburgUniversity Medical Center Hamburg-Eppendorf Hamburg Germany.
Paula MünklerDepartment of Cardiology University Heart and Vascular Center HamburgUniversity Medical Center Hamburg-Eppendorf Hamburg Germany.
Benjamin SchäfferDepartment of Cardiology University Heart and Vascular Center HamburgUniversity Medical Center Hamburg-Eppendorf Hamburg Germany.
Niklas KlattDepartment of Cardiology University Heart and Vascular Center HamburgUniversity Medical Center Hamburg-Eppendorf Hamburg Germany.
Christiane JungenDepartment of Cardiology University Heart and Vascular Center HamburgUniversity Medical Center Hamburg-Eppendorf Hamburg Germany.
Jannis DickowDepartment of Cardiology University Heart and Vascular Center HamburgUniversity Medical Center Hamburg-Eppendorf Hamburg Germany.
Annika TamenangDepartment of Cardiology University Heart and Vascular Center HamburgUniversity Medical Center Hamburg-Eppendorf Hamburg Germany.
Ruben SchlebergerDepartment of Cardiology University Heart and Vascular Center HamburgUniversity Medical Center Hamburg-Eppendorf Hamburg Germany.
Simon PechaDepartment of Cardiovascular Surgery University Heart and Vascular Center HamburgUniversity Medical Center Hamburg-Eppendorf Hamburg Germany.
Hans Pinnschmidt3Institute of Medical Biometry and Epidemiology - University Medical Center Hamburg-Eppendorf Hamburg Germany.
Monica PattenDepartment of Cardiology University Heart and Vascular Center HamburgUniversity Medical Center Hamburg-Eppendorf Hamburg Germany.
Hermann ReichenspurnerDepartment of Cardiovascular Surgery University Heart and Vascular Center HamburgUniversity Medical Center Hamburg-Eppendorf Hamburg Germany.
Stephan WillemsDepartment of Cardiology Asklepios Hospital St. Georg Hamburg Germany.
Christian MeyerDepartment of Cardiology University Heart and Vascular Center HamburgUniversity Medical Center Hamburg-Eppendorf Hamburg Germany.
Universität Hamburg · DEAsklepios Klinik St. Georg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background Atrial fibrillation (AF) is common in patients with hypertrophic cardiomyopathy (HCM) and is associated with a deterioration of clinical status. Ablation of symptomatic AF is an established therapy, but in HCM, the characteristics of recurrent atrial arrhythmias and the long-term outcome are uncertain. Methods and Results Sixty-five patients with HCM (aged 64.5±9.9 years, 42 [64.6%] men) underwent AF ablation. The ablation strategy included pulmonary vein isolation in all patients and ablation of complex fractionated atrial electrograms or subsequent atrial tachycardias (AT) if appropriate. Paroxysmal, persistent AF, and a primary AT was present in 13 (20.0%), 51 (78.5%), and 1 (1.5%) patients, respectively. Twenty-five (38.4%) patients developed AT with a total number of 54 ATs. Stable AT was observed in 15 (23.1%) and unstable AT in 10 (15.3%) patients. The mechanism was characterized as a macroreentry in 37 (68.5%), as a localized reentry in 12 (22.2%), a focal mechanism in 1 (1.9%), and not classified in 4 (7.4%) ATs. After 1.9±1.2 ablation procedures and a follow-up of 48.1±32.5 months, freedom of AF/AT recurrences was demonstrated in 60.0% of patients. No recurrences occurred in 84.6% and 52.9% of patients with paroxysmal and persistent AF, respectively (

Indexed as

Atrial FibrillationCardiomyopathy, HypertrophicCatheter AblationElectrophysiologic Techniques, CardiacFemaleFollow-Up StudiesHumansMaleMiddle AgedRecurrenceRetrospective StudiesRisk FactorsTime FactorsTreatment Outcomeablationatrial fibrillationatrial tachycardiacatheter ablationhypertrophic cardiomyopathy

Identifiers

PMID33455428
PMCPMC7955439
OpenAlexW3125727884

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.