Evidence map›Paper›PMID 33455417›Full record

ArticleCartilage2021

Patients with Osteoarthritis and Kashin-Beck Disease Display Distinct CpG Methylation Profiles in the

Rongqiang Zhang, Hao Guo, Xiaoli Yang, Dandan Zhang, Di Zhang, Qiang Li, Chen Wang, Xuena Yang, Yongmin Xiong

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cartilage, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. The Zebrafish Model to Understand Epigenetics in Renal Diseases.International journal of molecular sciences · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Rongqiang ZhangSchool of Public Health, Shaanxi University of Chinese Medicine, Xianyang, China.
Hao GuoInstitute of Key Laboratory of Trace Elements and Endemic Diseases, National Health Commission of the People's Republic of China, School of Public Health, Xi'an Jiaotong University Health Science Center, Xi'an, Shaanxi, China.
Xiaoli YangInstitute of Key Laboratory of Trace Elements and Endemic Diseases, National Health Commission of the People's Republic of China, School of Public Health, Xi'an Jiaotong University Health Science Center, Xi'an, Shaanxi, China.
Dandan ZhangInstitute of Key Laboratory of Trace Elements and Endemic Diseases, National Health Commission of the People's Republic of China, School of Public Health, Xi'an Jiaotong University Health Science Center, Xi'an, Shaanxi, China.
Di ZhangInstitute of Key Laboratory of Trace Elements and Endemic Diseases, National Health Commission of the People's Republic of China, School of Public Health, Xi'an Jiaotong University Health Science Center, Xi'an, Shaanxi, China.
Qiang LiInstitute of Key Laboratory of Trace Elements and Endemic Diseases, National Health Commission of the People's Republic of China, School of Public Health, Xi'an Jiaotong University Health Science Center, Xi'an, Shaanxi, China.
Chen WangInstitute of Key Laboratory of Trace Elements and Endemic Diseases, National Health Commission of the People's Republic of China, School of Public Health, Xi'an Jiaotong University Health Science Center, Xi'an, Shaanxi, China.
Xuena YangInstitute of Key Laboratory of Trace Elements and Endemic Diseases, National Health Commission of the People's Republic of China, School of Public Health, Xi'an Jiaotong University Health Science Center, Xi'an, Shaanxi, China.
Yongmin XiongInstitute of Key Laboratory of Trace Elements and Endemic Diseases, National Health Commission of the People's Republic of China, School of Public Health, Xi'an Jiaotong University Health Science Center, Xi'an, Shaanxi, China.ORCID 0000-0002-8263-2970
National Health and Family Planning Commission · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveWe aimed to analyze deoxycytidine-deoxyguanosine dinucleotide (CpGs) methylation profiles in

methodsBlood samples were collected from 16 primary OA patients and corresponding 16 healthy individuals and analyzed for methylations in the CpGs of

results

conclusionOA and KBD patients display distinct methylation profiles in the CpG sites of

Indexed as

Glutathione PeroxidaseIodide PeroxidaseThioredoxin Reductase 1AgedCase-Control StudiesDNA MethylationEpigenesis, GeneticHumansIodothyronine Deiodinase Type IIKashin-Beck DiseaseMiddle AgedOsteoarthritisPromoter Regions, GeneticSelenoproteinsGlutathione PeroxidaseGPX3 protein, humanIodide PeroxidaseIodothyronine Deiodinase Type IISelenoproteinsThioredoxin Reductase 1TXNRD1 protein, humanCpGCpG-SNPDNA methylationKashin-Beck diseaseosteoarthritis

Identifiers

PMID33455417
PMCPMC8808858
OpenAlexW3123205278

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.