Evidence map›Paper›PMID 33455379›Full record

ArticleACS biomaterials science & engineering2020

Coating Topologically Complex Electrospun Fibers with Nanothin Silk Fibroin Enhances Neurite Outgrowth in Vitro.

Alexis M Ziemba, Tanner D Fink, Mary Clare Crochiere, Devan L Puhl, Samichya Sapkota, Ryan J Gilbert, R Helen Zha

Open access · greenAbstract read
In one paragraph

Article in ACS biomaterials science & engineering, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 33 citations in OpenAlex.

  1. Review
  2. [Research progress on silk fibroin-nerve guidance conduits for peripheral nerve injury repair].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Alexis M ZiembaCenter for Biotechnology and Interdisciplinary Sciences, Rensselaer Polytechnic Institute, 1623 15th Street, Troy, New York 12180, United States.ORCID 0000-0001-8947-9617
Tanner D FinkCenter for Biotechnology and Interdisciplinary Sciences, Rensselaer Polytechnic Institute, 1623 15th Street, Troy, New York 12180, United States.
Mary Clare CrochiereCenter for Biotechnology and Interdisciplinary Sciences, Rensselaer Polytechnic Institute, 1623 15th Street, Troy, New York 12180, United States.
Devan L PuhlCenter for Biotechnology and Interdisciplinary Sciences, Rensselaer Polytechnic Institute, 1623 15th Street, Troy, New York 12180, United States.ORCID 0000-0002-8293-3415
Samichya SapkotaCenter for Biotechnology and Interdisciplinary Sciences, Rensselaer Polytechnic Institute, 1623 15th Street, Troy, New York 12180, United States.
Ryan J GilbertCenter for Biotechnology and Interdisciplinary Sciences, Rensselaer Polytechnic Institute, 1623 15th Street, Troy, New York 12180, United States.ORCID 0000-0002-3501-6753
R Helen ZhaCenter for Biotechnology and Interdisciplinary Sciences, Rensselaer Polytechnic Institute, 1623 15th Street, Troy, New York 12180, United States.ORCID 0000-0002-0766-5705
Rensselaer Polytechnic Institute · US

Funding

Enhanced Neuroprotection Following Acute SCI Using Fibrous MaterialsR01NS092754 · NINDS · RENSSELAER POLYTECHNIC INSTITUTE · PI GILBERT, RYAN J. · 2015 to 2019
$1.3M
NINDS NIH HHS R01 NS092754
6 · The paper itself

Abstract

Electrospun poly-l-lactic acid (PLLA) fibers are commonly used for tissue engineering applications because of their uniform morphology, and their efficacy can be further enhanced via surface modification. In this study, we aimed to increase neurite outgrowth along electrospun fibers by coating with silk fibroin (SF), a bioinert protein derived from

Indexed as

FibroinsAnimalsNerve RegenerationNeuronal OutgrowthTissue EngineeringTissue ScaffoldsFibroinsdorsal root gangliaelectrospun fiberneurite outgrowthpoly-l-lactic acidsilk fibroin

Identifiers

PMID33455379
PMCPMC8275559
OpenAlexW3005072452

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.