Evidence map›Paper›PMID 33454904›Full record

ArticleMolecular biology reports2021

Preadministration of yerba mate (Ilex paraguariensis) helps functional activity and morphology maintenance of MC3T3-E1 osteoblastic cells after in vitro exposition to hydrogen peroxide.

Gabrielli Collasanto Ceverino, Paula Katherine Vargas Sanchez, Roger Rodrigo Fernandes, Guilherme Alvarenga Alves, José Bernardo de Santis, Milla Sprone Tavares, Selma Siéssere, Karina Fittipaldi Bombonato-Prado

Abstract read
PubMed Publisher
In one paragraph

Article in Molecular biology reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 10 citations in OpenAlex.

  1. Protective Effects ofPharmaceuticals (Basel, Switzerland) · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Gabrielli Collasanto CeverinoDepartment of Basic and Oral Biology, Bone Research Lab, School of Dentistry of Ribeirão Preto, University of São Paulo, Ribeirão Preto, SP, Brazil.ORCID https://orcid.org/0000-0001-7183-895X
Paula Katherine Vargas SanchezUnit of Basic Oral Investigation-UIBO, School of Dentistry, Universidad El Bosque, Bogotá, Colombia.ORCID https://orcid.org/0000-0002-6554-4741
Roger Rodrigo FernandesDepartment of Oral and Maxillofacial Surgery and Periodontology, School of Dentistry of Ribeirão Preto, University of São Paulo, Ribeirão Preto, SP, Brazil.ORCID https://orcid.org/0000-0002-9245-1823
Guilherme Alvarenga AlvesDepartment of Basic and Oral Biology, Bone Research Lab, School of Dentistry of Ribeirão Preto, University of São Paulo, Ribeirão Preto, SP, Brazil.ORCID https://orcid.org/0000-0001-7064-5515
José Bernardo de SantisDepartment of Basic and Oral Biology, Bone Research Lab, School of Dentistry of Ribeirão Preto, University of São Paulo, Ribeirão Preto, SP, Brazil.ORCID https://orcid.org/0000-0001-7985-6343
Milla Sprone TavaresDepartment of Oral and Maxillofacial Surgery and Periodontology, School of Dentistry of Ribeirão Preto, University of São Paulo, Ribeirão Preto, SP, Brazil.ORCID https://orcid.org/0000-0002-6757-4995
Selma SiéssereDepartment of Basic and Oral Biology, Bone Research Lab, School of Dentistry of Ribeirão Preto, University of São Paulo, Ribeirão Preto, SP, Brazil.ORCID https://orcid.org/0000-0001-9756-3771
Karina Fittipaldi Bombonato-PradoDepartment of Basic and Oral Biology, Bone Research Lab, School of Dentistry of Ribeirão Preto, University of São Paulo, Ribeirão Preto, SP, Brazil. karina@forp.usp.br.ORCID http://orcid.org/0000-0002-0267-7643
Universidade de São Paulo · BRUniversidade de Ribeirão Preto · BRUniversidad El Bosque · CO

Funding

Fundação de Amparo à Pesquisa do Estado de São Paulo 2017/24679-3
6 · The paper itself

Abstract

Natural substances with antioxidant effects may benefit prevention and treatment of people with or prone to bone diseases after menopause, such as osteoporosis. This study aimed to evaluate the in vitro effect of preadministration of yerba mate extract (YM) in the metabolism of MC3T3-E1 osteoblasts exposed to hydrogen peroxide (H

Indexed as

3T3 CellsAnimalsAntioxidantsCell ProliferationHydrogen PeroxideIlex paraguariensisMiceOsteoblastsOxidative StressPlant ExtractsAntioxidantsHydrogen PeroxidePlant ExtractsHydrogen peroxideOsteoblastsYerba mate extract

Identifiers

PMID33454904
OpenAlexW3125440923

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.