Evidence map›Paper›PMID 33454764›Full record

ArticleAge and ageing2021

Dual impairments in visual and hearing acuity and age-related cognitive decline in older adults from the Rancho Bernardo Study of Healthy Aging.

Humberto Parada, Gail A Laughlin, Mingan Yang, Frances R Nedjat-Haiem, Linda K McEvoy

Abstract read
In one paragraph

Article in Age and ageing, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Dual sensory impairment: Global prevalence, future projections, and its association with cognitive decline.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025
    Pooled it
  2. Article
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  11. Sensory Loss and Risk of Dementia.The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry · 2024
    Review
  12. Article
  13. Article
  14. Article
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  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Humberto ParadaDivision of Epidemiology and Biostatistics, School of Public Health, San Diego State University, San Diego, CA, USA.
Gail A LaughlinDepartment of Family Medicine and Public Health, University of California San Diego, La Jolla, CA, USA.
Mingan YangDivision of Epidemiology and Biostatistics, School of Public Health, San Diego State University, San Diego, CA, USA.
Frances R Nedjat-HaiemSchool of Social Work, San Diego State University, San Diego, CA, USA.
Linda K McEvoyDepartment of Family Medicine and Public Health, University of California San Diego, La Jolla, CA, USA.

Funding

Research Education CoreU54CA132384 · NCI · SAN DIEGO STATE UNIVERSITY · PI CRIPPS, RICHARD MATTHEW, CROWE, SHEILA E. · 2008 to 2022
$20.7M
Research Education CoreU54CA132379 · NCI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI ARREDONDO, ELVA M, CROWE, SHEILA E. · 2008 to 2021
$16.1M
San Diego Resource Center for advancing Alzheimer's Research in Minority Seniors (ARMS)P30AG059299 · NIA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI JOHN P. ELDER, PAUL E GILBERT · 2018 to 2026
$7.4M
STUDY OF RISK FACTORS FOR OSTEOPOROSIS IN THE ELDERLYR37AG007181 · NIA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI BARRETT-CONNOR, ELIZABETH L · 1987 to 2010
$5.4M
Association of Alcohol and Nutrition with Cognition and Brain Structure in AgingR01AA021187 · NIAAA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI MCEVOY, LINDA KATHLEEN · 2013 to 2017
$2.9M
GENDER DIFFERENCES IN OSTEOPOROSISR01AG007181 · NIA · UNIVERSITY OF CALIFORNIA SAN DIEGO · PI BARRETT-CONNOR, ELIZABETH L · 1999 to 2002
$1.6M
Moderate alcohol use: risk or protective factor for age-related cognitive decline, mild cognitive impairment, and brain health in agingR01AG062483 · NIA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI MCEVOY, LINDA KATHLEEN · 2019 to 2021
$1.6M
CVD Predictors of Cognitive Function Trajectory over 20 YearsR01AG028507 · NIA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI BARRETT-CONNOR, ELIZABETH L · 2007 to 2010
$1.2M
Archiving the Rancho Bernardo Study of Healthy AgingRF1AG054067 · NIA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI LAUGHLIN, GAIL A, MCEVOY, LINDA KATHLEEN · 2016 to 2016
$1.2M
Red Blood Cell Polyunsaturated Fatty Acids and Breast Cancer Mortality in the Women's Healthy Eating and Living (WHEL) StudyK01CA234317 · NCI · SAN DIEGO STATE UNIVERSITY · PI PARADA, HUMBERTO · 2019 to 2023
$928k
EPIDEMIOLOGY OF NIDDM AND IGT IN AN ADULT COMMUNITYR01DK031801 · NIDDK · UNIVERSITY OF CALIFORNIA SAN DIEGO · PI BARRETT-CONNOR, ELIZABETH L · 1986 to 2000
$606k
A Prospective Study of Adiposity and Subclinical Coronary Artery DiseaseR21HL089622 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI WASSEL, CHRISTINA L. · 2009 to 2010
$425k
NCI NIH HHS K01 CA234317NCI NIH HHS L30 CA220767NCI NIH HHS U54 CA132379NCI NIH HHS U54 CA132384NHLBI NIH HHS R21 HL089622NIAAA NIH HHS R01 AA021187NIA NIH HHS P30 AG059299NIA NIH HHS R01 AG007181NIA NIH HHS R01 AG028507NIA NIH HHS R01 AG062483NIA NIH HHS R37 AG007181NIA NIH HHS RF1 AG054067NIDDK NIH HHS R01 DK031801NIH HHS HL089622
6 · The paper itself

Abstract

backgroundWe examined the associations between dual impairments in visual and hearing acuity and aging-related cognitive decline.

methodsThis was a longitudinal study of adults who had visual and hearing acuity and cognitive function assessed in 1992-1996 and were followed for up to 24 years (mean = 7.3 years), with up to five additional cognitive assessments. Visual impairment was defined as vision worse than 20/40, hearing impairment as pure-tone average thresholds >25 dB. Associations were tested using linear mixed-effects regressions.

resultsOf 1,383 participants, 293 had visual impairment, 990 had a hearing impairment and 251 had both deficits. In fully adjusted models, low visual acuity was associated with poorer Mini-Mental State Examination (MMSE; β = -0.29) and Trail-Making Test Part B (Trails B; β = 13.22) performance, and with faster declines in MMSE (β = -0.12) and Trails B (β = 1.84). The combination of low visual and low hearing acuity was associated with poorer MMSE (β = -0.44) and Trails B (β = 11.20) scores, and with faster declines in MMSE (β = -0.19), Trails B (β = 3.50), and Verbal Fluency Test (VFT; β = -0.14) performance. Associations were similar in men and women.

conclusionImpairments in both vision and hearing are associated with a more rapid decline in cognitive function with aging.

Indexed as

Cognitive DysfunctionHealthy AgingHearing LossAgedFemaleHearingHumansLongitudinal StudiesMaleVision Disorderscognitive aging, older peoplehearingsensory impairmentsvision

Identifiers

PMID33454764
PMCPMC8244568

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.