Evidence map›Paper›PMID 33454626›Full record

ArticleDrug and alcohol dependence2021

Dopamine D

David Matuskey, Gustavo A Angarita, Patrick Worhunsky, Sheida Koohsari, Paul Gravel, Brian Pittman, Edward C Gaiser, Jean-Dominque Gallezot, Nabeel Nabulsi, Yiyun Huang and 3 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Drug and alcohol dependence, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 53% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

David MatuskeyDepartment of Radiology and Biomedical Imaging, Yale University, New Haven, CT, United States; Department of Psychiatry, Yale University, New Haven, CT, United States; Department of Neurology, Yale University, New Haven, CT, United States. Electronic address: david.matuskey@yale.edu.
Gustavo A AngaritaDepartment of Psychiatry, Yale University, New Haven, CT, United States; Connecticut Mental Health Center, New Haven, CT, United States.
Patrick WorhunskyDepartment of Psychiatry, Yale University, New Haven, CT, United States.
Sheida KoohsariDepartment of Radiology and Biomedical Imaging, Yale University, New Haven, CT, United States.
Paul GravelDepartment of Radiology and Biomedical Imaging, Yale University, New Haven, CT, United States.
Brian PittmanDepartment of Psychiatry, Yale University, New Haven, CT, United States.
Edward C GaiserDepartment of Radiology and Biomedical Imaging, Yale University, New Haven, CT, United States.
Jean-Dominque GallezotDepartment of Radiology and Biomedical Imaging, Yale University, New Haven, CT, United States.
Nabeel NabulsiDepartment of Radiology and Biomedical Imaging, Yale University, New Haven, CT, United States.
Yiyun HuangDepartment of Radiology and Biomedical Imaging, Yale University, New Haven, CT, United States.
Richard E CarsonDepartment of Radiology and Biomedical Imaging, Yale University, New Haven, CT, United States.
Marc N PotenzaDepartment of Psychiatry, Yale University, New Haven, CT, United States; Connecticut Mental Health Center, New Haven, CT, United States; Connecticut Council on Problem Gambling, Wethersfield, CT, United States; Department of Neuroscience, Yale University, New Haven, CT, United States.
Robert T MalisonDepartment of Psychiatry, Yale University, New Haven, CT, United States; Connecticut Mental Health Center, New Haven, CT, United States.
Yale University · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Clinical Neuroscience Research Training Program in PsychiatryT32MH019961 · NIMH · YALE UNIVERSITY · PI Christopher John Pittenger · 1996 to 2026
$5.9M
Translational Research of Cocaine, Striatum, and ImpulsivitiesP20DA027844 · NIDA · YALE UNIVERSITY · PI TAYLOR, JANE R · 2010 to 2013
$3.6M
Patient-Oriented Research and Mentoring in the Translational Neurobiology/GeneticK24DA017899 · NIDA · YALE UNIVERSITY · PI MALISON, ROBERT T · 2007 to 2012
$827k
DBH, D2High and Cocaine Paranoia/Aversion: A [11C]PHNO PET StudyR03DA027456 · NIDA · YALE UNIVERSITY · PI MALISON, ROBERT T · 2009 to 2010
$420k
NCATS NIH HHS UL1 TR001863NIDA NIH HHS K24 DA017899NIDA NIH HHS L30 DA029943NIDA NIH HHS P20 DA027844NIDA NIH HHS R03 DA027456NIMH NIH HHS T32 MH019961
6 · The paper itself

Abstract

backgroundPositron emission tomography (PET) work with the dopamine D3 receptor (D

methodsNon-obese CUD subjects (N = 12) were compared to age-matched obese CUD subjects (N = 14). All subjects underwent [

resultsIn between-group analyses, D2/3R availability in non-obese and obese CUD groups was not significantly different overall. BMI was inversely correlated withBP

conclusionThese data suggest that obesity in CUD was not associated with significant differences in D

Indexed as

Positron-Emission TomographyAdultBody Mass IndexCocaine-Related DisordersGlobus PallidusHumansLigandsMiddle AgedObesityReceptors, Dopamine D2Receptors, Dopamine D3Substantia NigraVentral Tegmental AreaLigandsReceptors, Dopamine D2Receptors, Dopamine D3Addictive behaviorsCocaineDopamineObesityRewardSubstance-related disorders

Identifiers

PMID33454626
PMCPMC7889720
OpenAlexW3120866507

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.