SynthesisSystematic reviews2021
Factors that influence adherence to surgical antimicrobial prophylaxis (SAP) guidelines: a systematic review.
Synthesis in Systematic reviews, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
24 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- European Network for Optimization of Veterinary Antimicrobial Therapy (ENOVAT) 2025 guidelines for surgical antimicrobial prophylaxis in dogs and cats.The Journal of small animal practice · 2026Guideline
- The impact of antimicrobial stewardship interventions on appropriate use of surgical antimicrobial prophylaxis in low- and middle-income countries: a systematic review.Systematic reviews · 2024Pooled it
- Pooled it
- Article
- Patterns of Surgical Prophylaxis Prescribing for Dentoalveolar Procedures in Australian Hospitals: 2016-2022.Australian dental journal · 2026Article
- Pre-implementation safety evaluation of an AI decision-support system for surgical antimicrobial prophylaxis.Internal medicine journal · 2026Article
- Adherence to perioperative antimicrobial prophylaxis in cancer surgeries: A single-center retrospective study from Oman.IJID regions · 2026Article
- Adherence to guideline recommendations for postoperative atrial fibrillation: a nationwide survey reveals major prevention gaps.International journal of surgery (London, England) · 2026Article
- Infection control competency in surgical settings among clinical medical students in Sudan: a cross sectional study.BMC medical education · 2025Article
- Antimicrobial prophylaxis for endourological procedures in Jordanian hospitals: a multi-centre qualitative study.BMJ open · 2025Article
- A Point Prevalence Survey of antibiotics use patterns at Tanga Regional Referral Hospital in Tanzania.Antimicrobial stewardship & healthcare epidemiology : ASHE · 2025Article
- User perceptions of surgical antimicrobial prophylaxis guidelines in orthopaedic surgery in a tertiary Australian hospital.PloS one · 2025Article
- Article
- Reducing Improper and Missed Peri-Procedure Antibiotics Prescriptions in a Regional Oncology Centre.Cureus · 2024Article
- Assessment of antimicrobial prescribing patterns, guidelines compliance, and appropriateness of antimicrobial prescribing in surgical-practice units: point prevalence survey in Malaysian teaching hospitals.Frontiers in pharmacology · 2024Article
- Antibiotic use in spine surgery: A narrative review based in principles of antibiotic stewardship.North American Spine Society journal · 2023Article
- Impact of the Five-Year Intervention of an Antimicrobial Stewardship Program on the Optimal Selection of Surgical Prophylaxis in a Hospital without Antibiotic Prescription Restrictions in Costa Rica: A Retrospective Study.Antibiotics (Basel, Switzerland) · 2023Article
- "A breach in the protocol for no good reason": a surgical antimicrobial prophylaxis experience in an Ethiopian academic medical center.Perioperative medicine (London, England) · 2023Article
- Article
- Etiquette of the antibiotic decision-making process for surgical prophylaxis in Ethiopia: a triangulated ethnographic study.Frontiers in public health · 2023Observational
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDespite the extensive research that has been conducted to date, practice often differs from established guidelines and will vary between individuals and organisations. It has been noted that the global uptake of local and international surgical antimicrobial prophylaxis (SAP) guidelines is poor with limited research investigating factors that affect guideline adherence. The purpose of this systematic review was to determine the reported barriers and enablers to the adherence of SAP guidelines.
methodsA search of the literature was performed using four electronic databases (CINAHL, EMBASE, PubMed and SCOPUS) for articles published in the English language from January 1998 to December 2018. Articles were included if they were solely related to SAP and discussed the barriers or enablers to SAP guideline adherence. Articles that assessed the adherence to a range of infection control measures or discussed adherence to antibiotic treatment guidelines rather than SAP guidelines were excluded from this review. Barriers and enablers were mapped to the Theoretical Domains Framework (TDF). The Mixed Methods Appraisal Tool was used to assess the quality of included studies.
resultsA total of 1489 papers were originally retrieved, with 48 papers meeting the eligibility criteria. Barriers and enablers were mapped to 11 out of 14 TDF domains: knowledge, skills, social/professional role and identity, beliefs about capabilities, beliefs about consequences, reinforcement, memory, attention and decision processes, environmental context and resources, social influences, emotion and behavioural regulation. Barriers were further categorised into personal or organisational barriers, while enablers were arranged under commonly trialled interventions.
conclusionsThere are numerous factors that can determine the uptake of SAP guidelines. An identification and understanding of these factors at a local level is required to develop tailored interventions to enhance guideline adherence. Interventions, when used in combination, can be considered as a means of improving guideline use.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.