ReviewProgress in cardiovascular diseases
The physiological benefits of sitting less and moving more: Opportunities for future research.
Review in Progress in cardiovascular diseases. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 23 citations in OpenAlex.
- A study on Mahjong intervention to improve cognitive impairment in patients with schizophrenia: a pilot, single-blind, randomized, controlled trial.BMC psychiatry · 2025Trial
- Prevalence of sarcopenia among aging employees in a higher education institution.BMC musculoskeletal disorders · 2026Article
- A Work-Based, Fully Remote, and Peer-Supported Exercise Snack Behavior Change Intervention (MOV'D): Protocol for a Randomized Controlled Pilot Trial.JMIR research protocols · 2025Article
- 24-h movement guidelines and its association with health-related physical fitness in Brazilian adolescents.Sports medicine and health science · 2025Article
- Article
- A twin-driven analysis on early aging biomarkers and associations with sitting-time and physical activity.PloS one · 2024Article
- Article
- Is There Any Relationship between Physical Activity Levels and Academic Achievement? A Cross-Cultural Study among Spanish and Chilean Adolescents.Behavioral sciences (Basel, Switzerland) · 2023Article
- Physical activity in adults with epilepsy: clinical aspects and relationship with cognition and quality of life.Dementia & neuropsychologia · 2023Article
- Exercise, infection and rheumatic diseases: what do we know?RMD open · 2021Article
- Learning From Human Responses to Deconditioning Environments: Improved Understanding of the "Use It or Lose It" Principle.Frontiers in sports and active living · 2021Review
- Prolonged sedentary time under the state of emergency during the first wave of coronavirus disease 2019: Assessing the impact of work environment in Japan.Journal of occupational health · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 3 institutions in 1 country.
Funding
Abstract
Sedentary behavior (SB) and physical activity (PA) are important risk factors of cardiovascular disease morbidity and mortality. In addition to increasing the amount of moderate-to-vigorous PA (MVPA), the current PA guidelines recommend that adults should reduce SB, or any waking activity performed while sitting, reclining, or lying, with low energy expenditure. While mounting evidence has emphasized the benefits of increasing MVPA, little has focused on the effect of SB on health. Therefore, this review discusses the pathophysiological effects of SB and the potential physiological benefits of reducing/breaking up SB at the levels below the current guidelines for PA. Such knowledge is important, given that the majority of the United States population performs insufficient or no MVPA and is at high risk of being negatively impacted by SB. Interventions targeting sedentary time, such as breaking up SB by standing and moving, may be safe, feasible, and applicable to execute daily for a wide range of the population. This review also discusses the importance of monitoring SB in the era of the coronavirus disease 2019 (COVID-19) pandemic and the clinical implications of sitting less and moving more.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.