Evidence map›Paper›PMID 33453285›Full record

ReviewProgress in cardiovascular diseases

The physiological benefits of sitting less and moving more: Opportunities for future research.

Chueh-Lung Hwang, Szu-Hua Chen, Chih-Hsuan Chou, Georgios Grigoriadis, Tzu-Chieh Liao, Ibra S Fancher, Ross Arena, Shane A Phillips

Open access · greenAbstract readReview
In one paragraph

Review in Progress in cardiovascular diseases. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 23 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Chueh-Lung HwangDepartment of Physical Therapy, College of Applied Health Sciences, University of Illinois at Chicago, Chicago, IL, USA; Integrative Physiology Laboratory, College of Applied Health Sciences, University of Illinois at Chicago, Chicago, IL, USA.
Szu-Hua ChenDepartment of Physical Therapy, Ithaca College, Ithaca, NY, USA.
Chih-Hsuan ChouDepartment of Applied Physiology and Kinesiology, College of Health and Human Performance, Gainesville, FL, USA.
Georgios GrigoriadisDepartment of Physical Therapy, College of Applied Health Sciences, University of Illinois at Chicago, Chicago, IL, USA; Integrative Physiology Laboratory, College of Applied Health Sciences, University of Illinois at Chicago, Chicago, IL, USA.
Tzu-Chieh LiaoDepartment of Physical Therapy, University of Michigan-Flint, Flint, MI, USA.
Ibra S FancherDepartment of Kinesiology and Applied Physiology, College of Health Sciences, University of Delaware, Newark, DE, USA.
Ross ArenaDepartment of Physical Therapy, College of Applied Health Sciences, University of Illinois at Chicago, Chicago, IL, USA; Integrative Physiology Laboratory, College of Applied Health Sciences, University of Illinois at Chicago, Chicago, IL, USA; Healthy Living for Pandemic Event Protection (HL - PIVOT) Network, Chicago, IL, USA.
Shane A PhillipsDepartment of Physical Therapy, College of Applied Health Sciences, University of Illinois at Chicago, Chicago, IL, USA; Integrative Physiology Laboratory, College of Applied Health Sciences, University of Illinois at Chicago, Chicago, IL, USA; Healthy Living for Pandemic Event Protection (HL - PIVOT) Network, Chicago, IL, USA. Electronic address: shanep@uic.edu.
Ithaca College · USUniversity of Delaware · USUniversity of Michigan–Flint · US

Funding

Reducing blood pressure in mid-life adult binge drinkers: the role of microvascular function and sympathetic activityK99AA028537 · NIAAA · UNIVERSITY OF ILLINOIS AT CHICAGO · PI HWANG, CHUEH-LUNG · 2020 to 2021
$254k
NIAAA NIH HHS K99 AA028537
6 · The paper itself

Abstract

Sedentary behavior (SB) and physical activity (PA) are important risk factors of cardiovascular disease morbidity and mortality. In addition to increasing the amount of moderate-to-vigorous PA (MVPA), the current PA guidelines recommend that adults should reduce SB, or any waking activity performed while sitting, reclining, or lying, with low energy expenditure. While mounting evidence has emphasized the benefits of increasing MVPA, little has focused on the effect of SB on health. Therefore, this review discusses the pathophysiological effects of SB and the potential physiological benefits of reducing/breaking up SB at the levels below the current guidelines for PA. Such knowledge is important, given that the majority of the United States population performs insufficient or no MVPA and is at high risk of being negatively impacted by SB. Interventions targeting sedentary time, such as breaking up SB by standing and moving, may be safe, feasible, and applicable to execute daily for a wide range of the population. This review also discusses the importance of monitoring SB in the era of the coronavirus disease 2019 (COVID-19) pandemic and the clinical implications of sitting less and moving more.

Indexed as

COVID-19AccelerometryAdultEnergy MetabolismExerciseHumansRisk FactorsSedentary BehaviorArterial functionFitnessInactivitySedentary behavior

Identifiers

PMID33453285
PMCPMC8628304
OpenAlexW3119941869

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.