ArticleThe Journal of pediatrics2021
Associations Between Early Structural Magnetic Resonance Imaging, Hammersmith Infant Neurological Examination, and General Movements Assessment in Infants Born Very Preterm.
Article in The Journal of pediatrics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03345069 (Early Prediction of Cognitive and Motor Deficits Using Advanced MRI in Very Preterm Infants), which is not on this map. Cited by 17 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Early Prediction of Cognitive and Motor Deficits Using Advanced MRI in Very Preterm Infants
Who cites it
17 citing papers in PubMed, 37 citations in OpenAlex.
- Trunk Kinematics in Writhing and Fidgety Movements: A Pilot Study on Early Postural Control in Infants Using Computer Vision.Bioengineering (Basel, Switzerland) · 2026Article
- Severity of punctate white matter lesions in preterm infants: antecedents and cerebral palsy prediction.Pediatric research · 2025Article
- Relationship between early neurological function and motor skills in Brazilian preterm infants: a cross-sectional study.BMC pediatrics · 2025Article
- General Movements in Infants with Neurological Risk: Associations with Motor Development and Referral Patterns for Brain Magnetic Resonance Imaging.Children (Basel, Switzerland) · 2025Article
- A Simple MRI Score Predicts Pathological General Movements in Very Preterm Infants with Brain Injury-Retrospective Cohort Study.Children (Basel, Switzerland) · 2024Article
- Prenatal Opioid Exposure and Risk for Adverse Brain and Motor Outcomes in Infants Born Premature.The Journal of pediatrics · 2024Article
- Identifying and Evaluating Young Children with Developmental Central Hypotonia: An Overview of Systematic Reviews and Tools.Healthcare (Basel, Switzerland) · 2024Review
- Reliability, Knowledge Translation, and Implementability of the Spanish Version of the Hammersmith Infant Neurological Examination.Healthcare (Basel, Switzerland) · 2024Article
- Hammersmith Infant Neurological Examination Subscores Are Predictive of Cerebral Palsy.Pediatric neurology · 2024Article
- Structural connectivity at term equivalent age and language in preterm children at 2 years corrected.Brain communications · 2024Article
- Prenatal tobacco smoke exposure and risk of brain abnormalities on magnetic resonance imaging at term in infants born very preterm.American journal of obstetrics & gynecology MFM · 2023Article
- Smartphone application links severity of retinopathy of prematurity to early motor behavior in a cohort of high-risk preterm infants.Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus · 2023Article
- Assessing the Utility of Neonatal Screening Assessments in Early Diagnosis of Cerebral Palsy in Preterm Infants.Brain sciences · 2022Article
- Profile of minor neurological findings after perinatal asphyxia.Acta paediatrica (Oslo, Norway : 1992) · 2022Article
- Long-term predictivity of early neurological assessment and developmental trajectories in low-risk preterm infants.Frontiers in neurology · 2022Article
- Association between brain structural network efficiency at term-equivalent age and early development of cerebral palsy in very preterm infants.NeuroImage · 2021Article
- Effects of intraventricular hemorrhage on white matter microstructural changes at term and early developmental outcomes in infants born very preterm.Neuroradiology · 2021Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
Abstract
objectiveTo evaluate the prevalence and associations between structural magnetic resonance imaging (sMRI) injury/abnormality at term-equivalent age and absent fidgety General Movements Assessment (GMA) and abnormal Hammersmith Infant Neurological Examination (HINE) scores among infants born very preterm at 3-4 months of corrected age. STUDY
designThis prospective cohort study enrolled 392 infants born ≤2 weeks of gestation from 5 neonatal intensive care units in the greater Cincinnati area between September 2016 and October 2019. Infants completed sMRI at term-equivalent age and GMA and HINE at 3-4 months of corrected age. All assessors were blinded.
resultsOf 392 infants, 375 (96%) had complete data. Of these, 44 (12%) exhibited moderate or severe brain abnormalities, 17 (4.5%) had abnormal GMA, and 77 (20.3%) had abnormal HINE. Global and regional abnormality scores on sMRI were significantly correlated with GMA (R
conclusionsWe observed a low prevalence of moderate or severe brain abnormalities in survivors born very preterm in this geographically defined cohort. The much greater prevalence of abnormal motor examination on the HINE compared with GMA and their low correlation suggests that these tests evaluate different constructs and, thus, should be used in combination with sMRI rather than interchangeably.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.