Evidence map›Paper›PMID 33453190›Full record

Trial reportArchives of physical medicine and rehabilitation2021

Effect of Aerobic Exercise on Cardiopulmonary Responses and Predictors of Change in Individuals With Parkinson's Disease.

Amanda L Penko, Nicole M Zimmerman, Michael Crawford, Susan M Linder, Jay L Alberts

Open access · greenAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Archives of physical medicine and rehabilitation, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 4 pooled it
5.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 4 syntheses or guidelines pooled it, 29 citations in OpenAlex.

  1. Pooled it
  2. Guideline
  3. Pooled it
  4. Pooled it
  5. Trial
  6. Trial
  7. Article
  8. Review
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  11. Article
  12. Effect of Noninvasive Static Human Data on Maximum Data in Exercise.International journal of environmental research and public health · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Amanda L PenkoDepartment of Biomedical Engineering, Cleveland Clinic, Cleveland, Ohio.
Nicole M ZimmermanDepartment of Clinical Transformation, Cleveland Clinic, Cleveland, Ohio.
Michael CrawfordPreventive Cardiology, Cleveland Clinic, Cleveland, Ohio.
Susan M LinderDepartment of Biomedical Engineering, Cleveland Clinic, Cleveland, Ohio; Department of Physical Medicine and Rehabilitation, Cleveland Clinic, Cleveland, Ohio.
Jay L AlbertsDepartment of Biomedical Engineering, Cleveland Clinic, Cleveland, Ohio; Center for Neurological Restoration, Cleveland Clinic, Cleveland, Ohio. Electronic address: albertj@ccf.org.
Cleveland Clinic · US

Funding

The Cyclical Lower-extremity Exercise for Parkinson's TrialR01NS073717 · NINDS · CLEVELAND CLINIC LERNER COM-CWRU · PI ALBERTS, JAY L. · 2011 to 2023
$4.8M
NINDS NIH HHS R01 NS073717
6 · The paper itself

Abstract

objectiveTo determine the effect of aerobic exercise on maximal and submaximal cardiopulmonary responses and predictors of change in individuals with Parkinson's disease (PD).

designSingle-center, parallel-group, rater-blind study.

settingResearch laboratory.

participantsIndividuals with mild to moderate PD (N=100).

interventionParticipants were enrolled in a trial evaluating the effect of cycling on PD and randomized to either voluntary exercise (VE), forced exercise (FE), or a no exercise control group. The exercise groups were time and intensity matched and exercised 3×/wk for 8 weeks on a stationary cycle.

main outcome measuresCardiopulmonary responses were collected via gas analysis during a maximal graded exercise test at baseline and post intervention.

resultsExercise attendance was 97% and 93% for the FE and VE group, respectively. Average exercise heart rate reserve was 67%±11% for FE and 70%±10% for VE. No significant difference was present for change in peak oxygen consumption (VO

conclusionsPeak and submaximal cardiopulmonary function may improve after aerobic exercise in individuals with PD. Lower age, higher exercise cadence, and lower baseline VO

Indexed as

AdultAgedExerciseExercise TestFemaleHumansMaleMiddle AgedOxygen ConsumptionParkinson DiseaseSingle-Blind MethodSpirometryVital SignsExerciseExercise testOxygen consumptionParkinson's diseaseRehabilitation

Identifiers

PMID33453190
PMCPMC12993736
OpenAlexW3119549800

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.