Evidence map›Paper›PMID 33453048›Full record

ArticleHigh blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension2021

The Interdependence of Blood Pressure and Glucose in Vietnam.

Tran Thi Thu Nga, Christopher Leigh Blizzard, Luong Ngoc Khue, Truong Le Van Ngoc, Tran Quoc Bao, Petr Otahal, Mark R Nelson, Costan G Magnussen, Bui Van Tan, Velandai Srikanth and 6 more

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Article in High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 3 institutions in 3 countries.

Tran Thi Thu NgaMenzies Institute for Medical Research, University of Tasmania, Private Bag 23, Hobart, TAS, 7000, Australia.
Christopher Leigh BlizzardMenzies Institute for Medical Research, University of Tasmania, Private Bag 23, Hobart, TAS, 7000, Australia. Leigh.Blizzard@utas.edu.au.
Luong Ngoc KhueMedical Services Administration, Ministry of Health of the Socialist Republic of Vietnam, Hanoi, Vietnam.
Truong Le Van NgocMedical Services Administration, Ministry of Health of the Socialist Republic of Vietnam, Hanoi, Vietnam.
Tran Quoc BaoMedical Services Administration, Ministry of Health of the Socialist Republic of Vietnam, Hanoi, Vietnam.
Petr OtahalMenzies Institute for Medical Research, University of Tasmania, Private Bag 23, Hobart, TAS, 7000, Australia.
Mark R NelsonMenzies Institute for Medical Research, University of Tasmania, Private Bag 23, Hobart, TAS, 7000, Australia.
Costan G MagnussenMenzies Institute for Medical Research, University of Tasmania, Private Bag 23, Hobart, TAS, 7000, Australia.
Bui Van TanMenzies Institute for Medical Research, University of Tasmania, Private Bag 23, Hobart, TAS, 7000, Australia.
Velandai SrikanthDepartment of Medicine, Peninsula Clinical School, Central Clinical School, Monash University, Melbourne, Victoria, Australia.
Au Bich ThuyMenzies Institute for Medical Research, University of Tasmania, Private Bag 23, Hobart, TAS, 7000, Australia.
Ha Thai SonMedical Services Administration, Ministry of Health of the Socialist Republic of Vietnam, Hanoi, Vietnam.
Phung Ngoc HaiMenzies Institute for Medical Research, University of Tasmania, Private Bag 23, Hobart, TAS, 7000, Australia.
Tran Hoang MaiMenzies Institute for Medical Research, University of Tasmania, Private Bag 23, Hobart, TAS, 7000, Australia.
Michele CallisayaMenzies Institute for Medical Research, University of Tasmania, Private Bag 23, Hobart, TAS, 7000, Australia.
Seana GallMenzies Institute for Medical Research, University of Tasmania, Private Bag 23, Hobart, TAS, 7000, Australia.
University of Tasmania · AUMinistry of Health · VNMonash University · AU

Funding

National Health and Medical Research Council Boosting Dementia Leadership Research Fellowship APP1135761National Heart Foundation of Australia Future Leader Fellowship FLF100446The Atlantic Philanthropies Inc, United States G0015338
6 · The paper itself

Abstract

introductionModelling of associations of systolic blood pressure (BP) and blood glucose (BG) with their explanatory factors in separate regressions treats them as having independent biological mechanisms. This can lead to statistical inferences that are unreliable because the substantial overlap in their etiologic and disease mechanisms is ignored.

aimThis study aimed to examine the relationship of systolic blood pressure (BP) and blood glucose (BG) with measures of obesity and central fat distribution and other factors whilst taking account of the inter-dependence between them.

methodsParticipants (n = 14706, 53.5 % females) aged 25-64 years were selected by multi-stage stratified cluster sampling from eight provinces each representing one of the eight geographical regions of Vietnam. Measurements were made using the World Health Organization STEPS protocols.

resultsStructural modelling identified direct effects for BG (men P = 0.000, women P = 0.029), age (men P = 0.000, women P = 0.000) and body mass index (BMI) (men P = 0.000, women P = 0.000) in the estimation of systolic BP, and for systolic BP (men P = 0.036, women P = 0.000) and waist circumference (WC) (men P = 0.032, women P = 0.009) in the estimation of BG. There were indirect effects of age, cholesterol, physical activity and tobacco smoking via their influence on WC and BMI. The errors in estimation of systolic BP and BG were correlated (men P = 0.000, women P = 0.004), the stability indices (men 0.466, women 0.495) showed the non-recursive models were stable, and the proportion of variance explained was mid-range (men 0.553, women 0.579).

conclusionThis study provided statistical evidence of a feedback loop between systolic BP and BG. BMI and WC were confirmed to be their primary explanatory factors. Saturated fat intake and physical activity were identified as possible targets of intervention for overweight and obesity, and indirectly for reducing systolic BP and BG. Harmful/hazardous alcohol intake was identified as a target of intervention for systolic BP.

Indexed as

AdiposityBlood PressureAdultBiomarkersBlood GlucoseBody Mass IndexFemaleGlucose Metabolism DisordersHumansHypertensionMaleMiddle AgedObesityPrognosisRisk AssessmentRisk FactorsBiomarkersBlood GlucoseBlood glucoseBlood pressureInter-relationship

Identifiers

PMID33453048
OpenAlexW3121597794

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.