Evidence map›Paper›PMID 33452917›Full record

ArticleEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2021

Prognostic capacity of the weighted lymph node ratio in head and neck squamous cell carcinoma patients treated with salvage neck dissection.

Eduard David Neumann, Aina Sansa, María Casasayas, Alfons Gutierrez, Miquel Quer, Xavier León

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In one paragraph

Article in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.8field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. PATH classification: a proposal for patients with HNSCC treated with salvage surgery.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Eduard David NeumannOtorhinolaryngology and Head and Neck Surgery Department, Hospital de La Santa Creu I Sant Pau, Universitat Autònoma de Barcelona, C/ Mas Casanovas, 90, 08041, Barcelona, Spain. eneumann@santpau.cat.ORCID http://orcid.org/0000-0003-1618-2067
Aina SansaOtorhinolaryngology and Head and Neck Surgery Department, Hospital Parc Taulí, Universitat Autònoma de Barcelona, Sabadell, Spain.
María CasasayasOtorhinolaryngology and Head and Neck Surgery Department, Hospital de La Santa Creu I Sant Pau, Universitat Autònoma de Barcelona, C/ Mas Casanovas, 90, 08041, Barcelona, Spain.
Alfons GutierrezOtorhinolaryngology and Head and Neck Surgery Department, Hospital de La Santa Creu I Sant Pau, Universitat Autònoma de Barcelona, C/ Mas Casanovas, 90, 08041, Barcelona, Spain.
Miquel QuerOtorhinolaryngology and Head and Neck Surgery Department, Hospital de La Santa Creu I Sant Pau, Universitat Autònoma de Barcelona, C/ Mas Casanovas, 90, 08041, Barcelona, Spain.
Xavier LeónOtorhinolaryngology and Head and Neck Surgery Department, Hospital de La Santa Creu I Sant Pau, Universitat Autònoma de Barcelona, C/ Mas Casanovas, 90, 08041, Barcelona, Spain.
Universitat Autònoma de Barcelona · ES

Funding

Instituto de Salud Carlos III (ES) FIS PI19/01661
6 · The paper itself

Abstract

purposeThe aim of the study was to assess the prognostic capacity of the recently described weighted lymph node ratio (WLNR) in patients with head and neck squamous cell carcinoma (HNSCC) who undergo salvage neck dissection for regional recurrence. MATERIAL AND

methodsWe retrospectively studied 197 adult patients with head and neck squamous cell carcinoma treated with salvage neck dissection from 1990 to 2017.

resultsThe mean value for the WLNR for all patients was 26.2%. We established a classification based on the WLNR values taking 10.8% as the cut-off point. Five-year disease-specific survival for patients with WLNR ≤ 10.8% (n = 89, 45.2%) was 39.9% (IC 95% 29.4-50.4%), and for patients with WLNR ≥ 10.8% (n = 108, 54.8%) it was 20.5% (IC 95% 12.3-28.7%) (p = 0.007). The multivariate analysis showed the WLNR had a significant prognostic capacity.

conclusionsAs a variable that integrates data related to the number of metastatic nodes with extracapsular spread to the LNR, the WLNR has a prognostic value in the pathological assessment of HNSCC patients with regional recurrence treated with salvage neck dissection.

Indexed as

Carcinoma, Squamous CellHead and Neck NeoplasmsHumansLymphatic MetastasisLymph Node RatioLymph NodesNeck DissectionNeoplasm Recurrence, LocalNeoplasm StagingPrognosisRetrospective StudiesSquamous Cell Carcinoma of Head and NeckExtracapsular spreadLymph node ratioPrognostic capacitySalvage neck dissection

Identifiers

PMID33452917
OpenAlexW3123201158

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.