Evidence map›Paper›PMID 33452911›Full record

SynthesisWorld journal of urology2021

Available active surveillance follow-up protocols for small renal mass: a systematic review.

Giacomo Rebez, Nicola Pavan, M Carmen Mir

Open access · bronzeAbstract readSystematic Review
PubMed Publisher
In one paragraph

Synthesis in World journal of urology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
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  11. Canadian Urological Association guideline: Management of small renal masses - Full-text.Canadian Urological Association journal = Journal de l'Association des urologues du Canada · 2022
    Article
  12. Renal cancer: overdiagnosis and overtreatment.World journal of urology · 2021
    Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Giacomo RebezUrology Clinic, Department of Medical, Surgical and Health Science, University of Trieste, Trieste, Italy.
Nicola PavanUrology Clinic, Department of Medical, Surgical and Health Science, University of Trieste, Trieste, Italy.
M Carmen MirDepartment of Urology, Fundacion Instituto Valenciano Oncologia, Valencia, Spain. mirmare@yahoo.es.ORCID http://orcid.org/0000-0002-1391-1378
University of Trieste · ITFundación Instituto Valenciano de Oncología · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo evaluate follow-up strategies for active surveillance of renal masses and to assess contemporary data.

methodsWe performed a comprehensive search of electronic databases (Embase, Medline, and Cochrane). A systematic review of the follow-up protocols was carried out. A total of 20 studies were included.

resultOur analysis highlights that most of the series used different protocols of follow-up without consistent differences in the outcomes. Most common protocol consisted in imaging and clinical evaluation at 3, 6, and 12 months and yearly thereafter. Median length of follow-up was 42 months (range 1-137). Mean age was 74 years (range 67-83). Of 2243 patients 223 (10%) died during the follow-up and 19 patients died of kidney cancer (0.8%). The growth rate was the most used parameter to evaluate disease progression eventually triggering delayed intervention. Maximal axial diameter was the most common method to evaluate growth rate. CT scan is the most used, probably because it is usually more precise than kidney ultrasound and more accessible than MRI. Performing chest X-ray at every check does not seem to alter the clinical outcome during AS.

conclusionThe minimal cancer-specific mortality does not seem to correlate with the follow-up scheme. Outside of growth rate and initial size, imaging features to predict outcome of RCC during AS are limited. Active surveillance of SRM is a well-established treatment option. However, standardized follow-up protocols are lacking. Prospective, randomized, trials to evaluate the best follow-up strategies are pending.

Indexed as

Kidney NeoplasmsWatchful WaitingAgedClinical ProtocolsHealth Services for the AgedHumansTumor BurdenActive surveillanceAgingFollow-upGeriatricKidney mass elderlyOctogenarianSeniorSmall renal masses

Identifiers

PMID33452911
OpenAlexW3125347025

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.