ArticleAbdominal radiology (New York)2021
Magnetic resonance imaging improves the prediction of tumor staging in localized prostate cancer.
Article in Abdominal radiology (New York), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
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11 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.
- 10 mm (PI-RADS v2.1) versus 15 mm (PI-RADS v1.0) tumor capsule contact length in predicting extracapsular extension in prostate cancer: Meta-analysis and systematic review.Abdominal radiology (New York) · 2025Pooled it
- Article
- MRI assessment of seminal vesicle involvement by prostate cancer using T2 signal intensity and volume.Abdominal radiology (New York) · 2024Article
- Amide proton transfer imaging has added value for predicting extraprostatic extension in prostate cancer patients.Frontiers in oncology · 2024Article
- MRI characteristics and oncological follow-up of patients with ISUP grade group 4 or 5 prostate cancer.Abdominal radiology (New York) · 2024Article
- Imaging classification of prostate cancer with extracapsular extension and its impact on positive surgical margins after laparoscopic radical prostatectomy.Frontiers in oncology · 2024Article
- The Diagnostic Performance of Tumor Stage on MRI for Predicting Prostate Cancer-Positive Surgical Margins: A Systematic Review and Meta-Analysis.Diagnostics (Basel, Switzerland) · 2023Review
- Imaging features of the PI-RADS for predicting extraprostatic extension of prostate cancer: systematic review and meta-analysis.Insights into imaging · 2023Article
- Pre-operative magnetic resonance imaging can predict prostate cancer with risk for positive surgical margins.Abdominal radiology (New York) · 2022Article
- Quantitative imaging parameters to predict the local staging of prostate cancer in intermediate- to high-risk patients.Insights into imaging · 2022Article
- Less qualitative multiparametric magnetic resonance imaging in prostate cancer can underestimate extraprostatic extension in higher grade tumors.International braz j urol : official journal of the Brazilian Society of UrologyArticle
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13 authors at 2 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
objectivesThe aim of this study was to investigate 3 Tesla multiparametric magnetic resonance imaging (mpMRI)-based predictors for the pretherapeutic T staging of prostate cancer and their accuracy.
methodsConsecutive patients with 3 Tesla mpMRI, positive systematic and MR-targeted biopsy, and subsequent radical prostatectomy (RPE) between 01/2016 and 12/2017 were included. MRI parameters such as measurable extraprostatic extension (EPE) (≥ 3 mm), length of (pseudo)capsular contact (LCC), invasion of neurovascular bundle (NVBI), and/or seminal vesicles lesion contact (SVC) or infiltration (SVI) were assessed and correlated to clinical and histopathological results.
results136 men were included. In 76 cases, a pT2 stage was determined, in 29 cases a pT3a, and in 31 a pT3b stage. The positive and negative predictive values (PPV, NPV) for the detection of T3 by measurable EPE on MRI was 98% (CI 0.88-1) and 81% (CI 0.72-0.87). No visible NVBI was found in pT2 patients (NPV 100%; CI 0.95-1). ROC analysis for T3a prediction with LCC (AUC 0.81) showed a sensitivity of 87% and a specificity of 62% at a threshold of 12.5 mm (J = 0.485) and 93% and 58% at 11 mm (J
conclusionsMRI-measurable EPE, LCC, and SVC were reliable, independent, preoperative predictors for a histopathological T3 stage. A LCC ≥ 11 mm indicated a pT3a stage, whereas a LCC < 5 mm excluded it. On MRI, visible SVI or even SVC of the PCa lesion was reliable preoperative predictors for a pT3b stage.
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