Evidence map›Paper›PMID 33452854›Full record

ArticleAmerican journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons2021

COVID-19 in pediatric kidney transplantation: The Improving Renal Outcomes Collaborative.

Charles Varnell, Lyndsay A Harshman, Laurie Smith, Chunyan Liu, Shiran Chen, Samhar Al-Akash, Gina-Marie Barletta, Craig Belsha, Paul Brakeman, Abanti Chaudhuri and 17 more

Open access · bronzeAbstract read
In one paragraph

Article in American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 3 pooled it
3.0field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 3 syntheses or guidelines pooled it, 49 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Impact of Respiratory Viral Infections in Transplant Recipients.Journal of the Pediatric Infectious Diseases Society · 2024
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Observational
  11. Article
  12. COVID-19 in pediatric lung transplant recipients: Clinical course and outcome.The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation · 2023
    Article
  13. Review
  14. AMMI Canada Practice Point on the treatment of acute COVID-19 in pediatrics.Journal of the Association of Medical Microbiology and Infectious Disease Canada = Journal officiel de l'Association pour la microbiologie medicale et l'infectiologie Canada · 2022
    Article
  15. Article
  16. Kidney implications of SARS-CoV2 infection in children.Pediatric nephrology (Berlin, Germany) · 2022
    Review
  17. Review
  18. Pediatric transplantation during the COVID-19 pandemic.World journal of transplantation · 2022
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

27 authors at 20 institutions in 1 country.

Charles VarnellCincinnati Children's Hospital Medical Center, Cincinnati, Ohio.ORCID 0000-0002-0409-3799
Lyndsay A HarshmanUniversity of Iowa Stead Family Children's Hospital, Iowa City, Iowa.
Laurie SmithCincinnati Children's Hospital Medical Center, Cincinnati, Ohio.
Chunyan LiuCincinnati Children's Hospital Medical Center, Cincinnati, Ohio.
Shiran ChenCincinnati Children's Hospital Medical Center, Cincinnati, Ohio.
Samhar Al-AkashDriscoll Children's Hospital, Corpus Christi, Texas.
Gina-Marie BarlettaPhoenix Children's Hospital, University of Arizona, Phoenix, Arizona.
Craig BelshaSSM Health Cardinal Glennon Children's Hospital, Saint Louis, Missouri.
Paul BrakemanDepartment of Pediatrics, University of California, San Francisco, California.
Abanti ChaudhuriLucile Packard Children's Hospital, Stanford University, Stanford, California.
Paul FadakarUPMC Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania.
Rouba GarroChildren's Healthcare of Atlanta, Emory School of Medicine, Atlanta, Georgia.
Caroline GluckNemours/Alfred I. duPont Hospital for Children, Wilmington, Delaware.
Jens GoebelChildren's Hospital Colorado, Aurora, Colorado.
David KershawC.S. Mott Children's Hospital, Ann Arbor, Michigan.
Debora MatossianAnn & Robert H. Lurie Children's Hospital of Chicago, Chicago, Illinois.ORCID 0000-0002-4463-9493
Corina NailescuRiley Hospital for Children at Indiana University Health, Indianapolis, Indiana.
Hiren P PatelNationwide Children's Hospital, Columbus, Ohio.
Cozumel PruetteJohns Hopkins University School of Medicine, Baltimore, Maryland.
Saritha RanabothuArkansas Children's Hospital, Little Rock, Arkansas.
Nancy RodigBoston Children's Hospital, Harvard Medical School, Boston, Massachusetts.ORCID 0000-0002-1471-7710
Jodi SmithSeattle Children's Hospital, Seattle, Washington.
Judith Sebestyen VanSickleChildren's Mercy Kansas City, Kansas City, Missouri.
Patricia WengUCLA Mattel Children's Hospital, Los Angeles, California.
Lara Danziger-IsakovCincinnati Children's Hospital Medical Center, Cincinnati, Ohio.ORCID 0000-0002-5691-5221
David K HooperCincinnati Children's Hospital Medical Center, Cincinnati, Ohio.ORCID 0000-0001-8732-4291
Michael SeifertUniversity of Alabama at Birmingham, Children's of Alabama, Birmingham, Alabama.ORCID 0000-0002-0557-6178
Cincinnati Children's Hospital Medical Center · USAlfred I. duPont Hospital for Children · USArkansas Children's Hospital · USBoston Children's Hospital · USCardinal Glennon Children’s Medical Center · USChildren's Healthcare of Atlanta · USChildren's Hospital Colorado · USChildren's Hospital of Pittsburgh · USChildren's Mercy Hospital · USChildren's of Alabama · USC. S. Mott Children's Hospital · USDriscoll Children's Hospital · USIndiana University Health · USJohns Hopkins University · USLucile Packard Children's Hospital · USLurie Children's Hospital · USMattel Children's Hospital · USNationwide Children's Hospital · USSeattle Children's Hospital · USUniversity of Arizona · US

Funding

KL2 Training ProgramKL2TR001426 · NCATS · UNIVERSITY OF CINCINNATI · PI ZELLER, MARGARET H · 2015 to 2024
$6.8M
Clinical and Molecular Biomarkers of Endpoints in Pediatric Renal TransplantationR01DK126807 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI SEIFERT, MICHAEL EDWARD · 2020 to 2024
$1.5M
NCATS NIH HHS 2KL2TR001426-05A1NCATS NIH HHS KL2 TR001426NIDDK NIH HHS R01 DK126807
6 · The paper itself

Abstract

There are limited data on the impact of COVID-19 in children with a kidney transplant (KT). We conducted a prospective cohort study through the Improving Renal Outcomes Collaborative (IROC) to collect clinical outcome data about COVID-19 in pediatric KT patients. Twenty-two IROC centers that care for 2732 patients submitted testing and outcomes data for 281 patients tested for SARS-CoV-2 by PCR. Testing indications included symptoms and/or potential exposures to COVID-19 (N = 134, 47.7%) and/or testing per hospital policy (N = 154, 54.8%). Overall, 24 (8.5%) patients tested positive, of which 15 (63%) were symptomatic. Of the COVID-19-positive patients, 16 were managed as outpatients, six received non-ICU inpatient care and two were admitted to the ICU. There were no episodes of respiratory failure, allograft loss, or death associated with COVID-19. To estimate incidence, subanalysis was performed for 13 centers that care for 1686 patients that submitted all negative and positive COVID-19 results. Of the 229 tested patients at these 13 centers, 10 (5 asymptomatic) patients tested positive, yielding an overall incidence of 0.6% and an incidence among tested patients of 4.4%. Pediatric KT patients in the United States had a low estimated incidence of COVID-19 disease and excellent short-term outcomes.

Indexed as

COVID-19Kidney TransplantationChildHumansIncidenceProspective StudiesSARS-CoV-2clinical research/practiceepidemiologyhealth services and outcomes researchinfection and infectious agentsinfectious diseasekidney transplantation/nephrologypediatrics

Identifiers

PMID33452854
PMCPMC8013281
OpenAlexW3124319534

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.