Evidence map›Paper›PMID 33452760›Full record

ArticleBrain and behavior2021

Maternal depression and childhood injury risk: A population-based cohort study in Denmark.

Bente Kjaer Lyngsøe, Trine Munk-Olsen, Claus Høstrup Vestergaard, Dorte Rytter, Kaj Sparle Christensen, Bodil Hammer Bech

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Article in Brain and behavior, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

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8citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Clinical characteristics and socioeconomic determinants of unintentional childhood injuries: An emergency department perspective.Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES · 2026
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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Bente Kjaer LyngsøeResearch Unit for General Practice, Aarhus, Denmark.ORCID 0000-0003-2647-5437
Trine Munk-OlsenNational Centre for Register-based Research, Aarhus University, Aarhus, Denmark.
Claus Høstrup VestergaardResearch Unit for General Practice, Aarhus, Denmark.
Dorte RytterDepartment of Public Health, Aarhus University, Aarhus, Denmark.
Kaj Sparle ChristensenResearch Unit for General Practice, Aarhus, Denmark.
Bodil Hammer BechResearch Unit for General Practice, Aarhus, Denmark.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsTo assess the association between different stages of maternal depression and injury risk in offspring aged 0-10 years.

methodsPopulation-based cohort study of all live-born children in Denmark from 1 January 1997 until 31 December 2013 (n = 1,064,387). Main outcome measure was emergency department contacts with a main diagnosis of injury coded as DS00-DT98 (chapter XIX) according to the ICD-10. All information was obtained from Danish national registries.

resultsMaternal depression was associated with higher injury hazard in the offspring throughout childhood compared to offspring of mothers with no history of depression. The strongest association was seen for the first year of life. First-time maternal depression was most strongly associated with injury in the child, especially in the first year of life (aHR = 1.70, 95% CI: 1.48-1.96). Children of mothers with relapse depression had 1.57 higher hazard of injury in the first year of life (aHR: 1.57, 95% CI: 1.44-1.70). Children of mothers with previously treated depression (postdepression) had 1.13 higher hazard of injury in the first year of life (aHR: 1.13, 95% CI: 1.09-1.17). Continuous treatment for depression was associated with a nonsignificant higher hazard of injuries in the first year of life (aHR: 1.06, 95% CI: 0.91-1.23).

conclusionsMaternal depression was associated with higher injury risk in the offspring, particularly in early childhood. The association persisted in children of mothers with relapse depression. Our results suggest that children of mothers with depression are vulnerable several years after depression onset and treatment cessation.

Indexed as

DepressionMothersChildChild, PreschoolCohort StudiesDenmarkFemaleHumansRegistriesAdolescentChildDelivery of Health CareDepressive DisorderMother-Child RelationsWounds and Injuries

Identifiers

PMID33452760
PMCPMC7994683

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.