Evidence map›Paper›PMID 33452520›Full record

ReviewInternational journal of impotence research2021

Role of regenerative therapies on erectile dysfunction after radical prostatectomy.

S T Hansen, M Lund, L D Ostergaard, L Lund

Abstract readReview
PubMed Publisher
In one paragraph

Review in International journal of impotence research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Male Sexual Dysfunction.Health psychology research · 2022
    Article
  3. Future directions in improving sexual function for prostate cancer patients.International journal of impotence research · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

S T HansenDepartment of Urology, Odense University Hospital, Odense, Denmark.ORCID http://orcid.org/0000-0001-7160-1530
M LundDepartment of Urology, Odense University Hospital, Odense, Denmark.
L D OstergaardDepartment of Urology, Odense University Hospital, Odense, Denmark.ORCID http://orcid.org/0000-0001-5981-367X
L LundDepartment of Urology, Odense University Hospital, Odense, Denmark. Lars.Lund@rsyd.dk.ORCID http://orcid.org/0000-0003-0391-9568
University of Southern Denmark · DKOdense University Hospital · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The present study provides a review of stem cell therapy as a treatment of erectile dysfunction from peer-reviewed human and animal trials. A literature search was conducted in PubMed-Medline, Scopus, Embase, and Cochrane databases. Tweenty-three animal studies and seven human studies in the period from 1st of January 2000 to 1st of Mai 2020 were included. The seven included human studies are primary phase one trials, and most of them treat erectile dysfunction following radical prostatectomy by injection of stem cells into the corpus cavernosum. The primary outcome measure in all human trials is safety and secondary can stem cells play a role in the recovery of erectile function. All studies conclude that it is safe to use stem cells and the majority of the studies demonstrate an improvement in erectile function. The results from both animal and human trials are promising for stem cells as a restorative treatment, but data from large randomized human phase two trials is missing before it can be concluded, that stem cells is an effective treatment for erectile dysfunction in humans.

Indexed as

Erectile DysfunctionAnimalsHumansMalePenile ErectionPenisProstateProstatectomy

Identifiers

PMID33452520
OpenAlexW3121414941

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.