ArticleNature plants2021
Glycine max NNL1 restricts symbiotic compatibility with widely distributed bradyrhizobia via root hair infection.
Article in Nature plants, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 50 papers.
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Who cites it
50 citing papers in PubMed.
- Review
- Deciphering the genetic basis of nodule number through integrative analysis of host genotype and endophytes.Journal of advanced research · 2026Article
- Functional Characterization ofPlants (Basel, Switzerland) · 2026Article
- Soybean GTPase RAC1 interacts with the rhizobial effector NopC to promote root nodulation and improve yield.Plant communications · 2026Article
- Coordination of PTI and ETI in legume-rhizobium mutualism.aBIOTECH · 2026Review
- Cyclophilin A-mediated cis/trans isomerization modulates RIN4 to control intracellular rhizobial infection in legumes.The New phytologist · 2026Article
- Microbial co-inoculation and extracellular vesicles: new frontiers for soybean productivity.Antonie van Leeuwenhoek · 2026Review
- A Specific Sinorhizobium Flagellin Suppresses Legume Nodulation Through Immune Activation.Plant biotechnology journal · 2026Article
- Identification of nodule number-related loci and the candidate gene GmbHLH135 in soybean under low phosphorus stress.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2026Article
- CRISPR-induced knockouts reveal a dual role for the soybean NFR5α gene in symbiotic nitrogen fixation and root hair development.The plant genome · 2026Article
- Development of user-selectable diverse sets of cultivated and wild soybean germplasm for genetic and breeding applications.The plant genome · 2026Article
- Effects of Soil Moisture Content and Rj Genotype Differences on Soybean Productivity and Soybean-nodulating Bradyrhizobial Occupancy.Microbes and environments · 2026Article
- Screening of Bradyrhizobium ottawaense with High NMicrobes and environments · 2026Article
- The SNL Histone Deacetylase-Binding Factor GmHE13 Is a Novel Regulator of Soybean Hypocotyl Elongation.Plant biotechnology journal · 2025Article
- Genetic design of soybean hosts and bradyrhizobial endosymbionts reduces NNature communications · 2025Article
- How Structural Variations Influence Crop Improvement.International journal of molecular sciences · 2025Review
- Functional Genomics: From Soybean to Legume.International journal of molecular sciences · 2025Review
- Enacting partner specificity in legume-rhizobia symbioses.aBIOTECH · 2025Review
- Article
- Article
Corrections and comments
- Erratum issued
Authors and funding
31 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Symbiosis between soybean (Glycine max) and rhizobia is essential for efficient nitrogen fixation. Rhizobial effectors secreted through the type-III secretion system are key for mediating the interactions between plants and rhizobia, but the molecular mechanism remains largely unknown. Here, our genome-wide association study for nodule number identified G. max Nodule Number Locus 1 (GmNNL1), which encodes a new R protein. GmNNL1 directly interacts with the nodulation outer protein P (NopP) effector from Bradyrhizobium USDA110 to trigger immunity and inhibit nodulation through root hair infection. The insertion of a 179 bp short interspersed nuclear element (SINE)-like transposon into GmNNL1 leads to the loss of function of GmNNL1, enabling bradyrhizobia to successfully nodulate soybeans through the root hair infection route and enhancing nitrogen fixation. Our findings provide important insights into the coevolution of soybean-bradyrhizobia compatibility and offer a way to design new legume-rhizobia interactions for efficient symbiotic nitrogen fixation.
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