Evidence map›Paper›PMID 33452449›Full record

ArticleScientific reports2021

A novel rabbit fixator made of a thermoplastic mask for awake imaging experiments.

Rencai Lu, Li Hou, Siyu Wang, Bo She, Hong He, Wentao Gao, Sidang Wang, Dongdong Xv, Yunhai Ji, Shasha Yang and 2 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Rencai Lu *PET-CT Center, the First People's Hospital of Yunnan Province, Kunming, 650032, Yunnan Province, China.
Li Hou *Department of Radiation, the First People's Hospital of Yunnan Province, Kunming, 650032, Yunnan Province, China.
Siyu WangPET-CT Center, the First People's Hospital of Yunnan Province, Kunming, 650032, Yunnan Province, China.
Bo ShePET-CT Center, the First People's Hospital of Yunnan Province, Kunming, 650032, Yunnan Province, China. 1471265639@qq.com.
Hong HePET-CT Center, the First People's Hospital of Yunnan Province, Kunming, 650032, Yunnan Province, China.
Wentao GaoPET-CT Center, the First People's Hospital of Yunnan Province, Kunming, 650032, Yunnan Province, China.
Sidang WangPET-CT Center, the First People's Hospital of Yunnan Province, Kunming, 650032, Yunnan Province, China.
Dongdong XvPET-CT Center, the First People's Hospital of Yunnan Province, Kunming, 650032, Yunnan Province, China.
Yunhai JiPET-CT Center, the First People's Hospital of Yunnan Province, Kunming, 650032, Yunnan Province, China.
Shasha YangPET-CT Center, the First People's Hospital of Yunnan Province, Kunming, 650032, Yunnan Province, China.
Zhaohui YangYunnan Key Laboratory of Primate Biomedical Research, Institute of Primate Translational Medicine, Kunming University of Science and Technology, Kunming, 650093, Yunnan Province, China.
Shaobo WangPET-CT Center, the First People's Hospital of Yunnan Province, Kunming, 650032, Yunnan Province, China. wshbo_98@126.com.
First People's Hospital of Yunnan Province · CNKunming University of Science and Technology · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to develop and validate a novel rabbit fixator made from a thermoplastic mask for awake imaging experiments. When heated in a hot-water bath at 65-70 °C for 2-5 min, the thermoplastic mask became soft and could be molded to fit over the entire body of an anesthetized rabbit (4 ml of 3% pentobarbital sodium solution by intramuscular injection). Twenty rabbits were randomly divided into fixator (n = 10) and anesthesia (n = 10) groups. The animals' vital signs, stress hormones (cortisol and adrenaline), and subjective image quality scores for the computed tomography (CT), positron emission tomography (PET), and magnetic resonance imaging (MRI) scanning were measured and compared. Phantom CT, MRI and PET studies were performed to assess the performance with and without the thermoplastic mask by using image agents at different concentrations or with different radioactivity. The respiration rate (RR), systolic blood pressure (SBP), diastolic blood pressure (DBP), peripheral capillary oxygen saturation (SpO

Indexed as

AnimalsComputed Tomography AngiographyDiagnostic ImagingFemaleImmobilizationMagnetic Resonance ImagingPhantoms, ImagingPositron-Emission TomographyRabbitsRestraint, PhysicalWakefulnessWhole Body Imaging

Identifiers

PMID33452449
PMCPMC7810717
OpenAlexW3122440868

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.