ArticleScientific reports2021
Optimal blood pressure for patients with chronic kidney disease: a nationwide population-based cohort study.
Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 14 citations in OpenAlex.
- The optimal blood pressure target in old and very old patients with hypertension.Age and ageing · 2026Article
- Intradialytic blood pressure instability and associated factors among hemodialysis patients in Somalia: a retrospective study.Frontiers in nephrology · 2026Article
- Observational
- Association of the Intensive Blood Pressure Target and Cardiovascular Outcomes in the Population With Chronic Kidney Disease: A Retrospective Study in Korea.Journal of the American Heart Association · 2024Article
- The Fruit and Veggies for Kidney Health Study: A Prospective Randomized Trial.Kidney medicine · 2023Article
- Myocardial Infarction, Stroke, and All-Cause Mortality according to Low-Density Lipoprotein Cholesterol Level in the Elderly, a Nationwide Study.Diabetes & metabolism journal · 2022Article
- Variability independent of mean blood pressure as a real-world measure of cardiovascular risk.EClinicalMedicine · 2022Article
- Tight Blood Pressure Control in Chronic Kidney Disease.Journal of cardiovascular development and disease · 2022Review
- Combination of Statin and Ezetimibe versus Statin Monotherapy on Cardiovascular Disease and Type 2 Diabetes Incidence among Adults with Impaired Fasting Glucose: a Propensity-Matched Nationwide Cohort Study.Journal of lipid and atherosclerosis · 2021Article
- Blood Pressure Control and its Determinants among Patients with Chronic Kidney Disease in a Nigerian Tertiary Hospital: A Cross-Sectional Study.Nigerian medical journal : journal of the Nigeria Medical AssociationArticle
- Implementation and Validation of a Novel Noninvasive blood Pressure Measurement Algorithm Based on Oscillometric Method with Obtaining International Hypertension Standards.Journal of medical signals and sensorsArticle
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The effect of blood pressure (BP) on the incident cardiovascular events, progression to end-stage renal disease (ESRD) and mortality were evaluated among chronic kidney disease (CKD) patients with and without antihypertensive treatment. This nationwide study used the Korean National Health Insurance Service-Health Screening Cohort data. The hazards of outcomes were analysed according to the systolic BP (SBP) or diastolic BP (DBP) among adults (aged ≥ 40 years) with CKD and without previous cardiovascular disease or ESRD (n = 22,278). The SBP and DBP were ≥ 130 mmHg and ≥ 80 mmHg in 10,809 (48.52%) and 11,583 (51.99%) participants, respectively. During a median 6.2 years, 1271 cardiovascular events, 201 ESRD incidents, and 1061 deaths were noted. Individuals with SBP ≥ 130 mmHg and DBP ≥ 80 mmHg had higher hazards of hypertension-related adverse outcomes compared to the references (SBP 120-129 mmHg and DBP 70-79 mmHg). SBP < 100 mmHg was associated with hazards of all-cause death, and composite of ESRD and all-cause death during follow-up only among the antihypertensive medication users suggesting that the BP should be < 130/80 mmHg and the SBP should not be < 100 mmHg with antihypertensive agents to prevent the adverse outcome risk of insufficient and excessive antihypertensive treatment in CKD patients.
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