Evidence map›Paper›PMID 33452339›Full record

ArticleScientific reports2021

Urinary bisphenol A concentrations and the risk of obesity in Korean adults.

Shinje Moon, Moon Young Seo, Kyungho Choi, Yoon-Seok Chang, Shin-Hye Kim, Mi Jung Park

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.

  1. Pooled it
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  8. Review
  9. Analysis of Blood Biochemistry and Pituitary-Gonadal Histology after Chronic Exposure to Bisphenol-A of Mice.International journal of environmental research and public health · 2022
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Shinje MoonDepartment of Internal Medicine, Kangnam Sacred Heart Hospital, Hallym University Medical Center, Hallym University College of Medicine, Seoul, 07441, Republic of Korea.
Moon Young SeoDepartment of Pediatrics, Sanggye Paik Hospital, Inje University College of Medicine, 1342, Dongilro, Nowon-gu, Seoul, 01757, Korea.
Kyungho ChoiDepartment of Environmental Health Sciences, Seoul National University, Seoul, 08826, Republic of Korea.
Yoon-Seok ChangDivision of Environmental Science and Engineering, Pohang University of Science and Technology (Postech), Pohang, 37673, Republic of Korea.
Shin-Hye KimDepartment of Pediatrics, Sanggye Paik Hospital, Inje University College of Medicine, 1342, Dongilro, Nowon-gu, Seoul, 01757, Korea. S2635@paik.ac.kr.
Mi Jung ParkDepartment of Pediatrics, Sanggye Paik Hospital, Inje University College of Medicine, 1342, Dongilro, Nowon-gu, Seoul, 01757, Korea. PMJ@paik.ac.kr.
Inje University Sanggye Paik Hospital · KRHallym University Kangnam Sacred Heart Hospital · KRPohang University of Science and Technology · KRSeoul National University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study was aimed to evaluate the association between urinary bisphenol A (BPA) levels and risk of obesity in Korean adults. We analyzed data from the Korean National Environmental Health Survey (KoNEHS) Cycle 2 (2012-2014) and Cycle 3 (2015-2017). A total of 10,021 participants aged ≥ 19 years were included. Urine dilution was corrected by the covariate-adjusted standardization (CAS) method. We performed meta-analysis, logistic regression analysis by matching all covariates with a 1:1 propensity score, and a 4-knot restricted cubic spline plot model to calculate the odds ratios (ORs) for obesity according to natural log-transformed BPA levels. Mean urinary BPA concentration was 1.12 µg/L in KoNEHS Cycle 2 and 1.32 µg/L in Cycle 3. BPA levels were significantly higher among obese adults than among non-obese adults in both KoNEHS Cycles 2 and 3. In pooled data of KoNEHS Cycles 2 and 3, BPA showed significant positive associations with ORs for obesity in both sexes, which were more prominent in females (linear) than in males (non-linear). These associations were confirmed in spline analyses. CAS-applied BPA concentrations were positively associated with obesity in nationwide representative samples of Korean adults. Further studies are warranted to confirm and elucidate the underlying mechanism.

Indexed as

AdultAgedBenzhydryl CompoundsBisphenol A CompoundsBody Mass IndexFemaleHealth SurveysHumansLogistic ModelsMaleMiddle AgedObesityPhenolsPropensity ScoreRepublic of KoreaRisk FactorsBenzhydryl Compoundsbisphenol ABisphenol A CompoundsPhenols

Identifiers

PMID33452339
PMCPMC7811011
OpenAlexW3125391263

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.