ArticleNature communications2021
Inositol pyrophosphates promote the interaction of SPX domains with the coiled-coil motif of PHR transcription factors to regulate plant phosphate homeostasis.
Article in Nature communications, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 104 papers.
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Who cites it
104 citing papers in PubMed, 214 citations in OpenAlex.
- Arabidopsis inositol polyphosphate kinase activities regulate COP9 deneddylation functions in phosphate homeostasis.Journal of integrative plant biology · 2026Article
- SlMED25-SlPHR3-SlSPX2 module fine-tunes SlPHR3-mediated transcriptional activation of phosphate starvation response in tomato.Journal of integrative plant biology · 2026Article
- Sulfur in dialogue with phosphorus, nitrogen, and iron: regulatory networks in plant nutrient homeostasis.Journal of experimental botany · 2026Review
- Darkness Attenuates the Early Transcriptional Response to Phosphate Deficiency in Soybean Roots.International journal of molecular sciences · 2026Article
- Protein pyrophosphorylation by inositol pyrophosphates - detection, function, and regulation.FEBS letters · 2026Review
- Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates.FEBS letters · 2026Review
- Review
- Natural and CRISPR/Cas9 Editing Variations of Dual-uORFs Synergistically Increase the Nutritional Value of Silage Maize Feed.Plant biotechnology journal · 2026Article
- The PHO1 protein family in phosphate export and beyond.Plant physiology · 2026Review
- Structure-informed engineering of plant-microbe interactions.The Plant journal : for cell and molecular biology · 2026Review
- Article
- The SPX protein family in plants: from phosphate sensors to multifunctional signaling hubs.Stress biology · 2026Review
- Article
- Affinity-Based Interactome Mapping of Inositol Pyrophosphates Reveals 4/6-PP-InsPAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- PHR1 mediates rapid high light responses and acclimation to high photosynthetic activity.The Plant journal : for cell and molecular biology · 2026Article
- PPSR1 Protein Functions as an Important Regulator to Enhance Plant Growth Performance Under N, P, and K Deficient Stress Conditions.Plant biotechnology journal · 2026Article
- Multi-Omics Reveals Domestication-Associated Shifts in Phosphorus Adaptation Strategies in Tomato.Plants (Basel, Switzerland) · 2026Article
- The intracellular inositol (pyro)phosphate receptor AtSPX1 reciprocally binds to P1BS DNA.Nature communications · 2026Article
- Article
- Mesophyll protoplasts: a key tool for deciphering plant nutrient starvation pathways.Frontiers in plant science · 2026Article
44 more citing papers are in PubMed but not listed here.
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Authors and funding
12 authors at 5 institutions in 4 countries.
Funding
Abstract
Phosphorus is an essential nutrient taken up by organisms in the form of inorganic phosphate (Pi). Eukaryotes have evolved sophisticated Pi sensing and signaling cascades, enabling them to stably maintain cellular Pi concentrations. Pi homeostasis is regulated by inositol pyrophosphate signaling molecules (PP-InsPs), which are sensed by SPX domain-containing proteins. In plants, PP-InsP-bound SPX receptors inactivate Myb coiled-coil (MYB-CC) Pi starvation response transcription factors (PHRs) by an unknown mechanism. Here we report that a InsP
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