Evidence map›Paper›PMID 33452254›Full record

ArticleNature communications2021

Sequencing of the Arabidopsis NOR2 reveals its distinct organization and tissue-specific rRNA ribosomal variants.

Jason Sims, Giovanni Sestini, Christiane Elgert, Arndt von Haeseler, Peter Schlögelhofer

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 47 citations in OpenAlex.

  1. Dynamic evolution and hierarchical regulation of rDNA in polyploid oat.The Plant journal : for cell and molecular biology · 2026
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  5. Review
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  7. Regulation of nucleolar dominance through allopolyploidization of hexaploid wheat.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025
    Article
  8. Assessing Human Ribosomal DNA Variation and Its Association With Phenotypic Outcomes.BioEssays : news and reviews in molecular, cellular and developmental biology · 2025
    Review
  9. Ribosome-associated proteins: unwRAPping ribosome heterogeneity in the twenty-first century.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2025
    Review
  10. Article
  11. Article
  12. Article
  13. Transcriptional Silencing of 35S rDNA inInternational journal of molecular sciences · 2024
    Article
  14. Article
  15. Article
  16. Article
  17. Reaching for the off switch in nucleolar dominance.The Plant journal : for cell and molecular biology · 2023
    Article
  18. 45S rDNA DiversityPlants (Basel, Switzerland) · 2023
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Jason Sims *Department of Chromosome Biology, Max Perutz Labs, University of Vienna, Vienna BioCenter, Vienna, Austria. jason.sims@univie.ac.at.ORCID 0000-0003-4235-2488
Giovanni Sestini *Department of Chromosome Biology, Max Perutz Labs, University of Vienna, Vienna BioCenter, Vienna, Austria.ORCID 0000-0002-6643-7585
Christiane ElgertCenter for Integrative Bioinformatics Vienna (CIBIV), Max Perutz Labs, University of Vienna and Medical University of Vienna, Vienna BioCenter, Vienna, Austria.ORCID 0000-0003-2539-0394
Arndt von HaeselerCenter for Integrative Bioinformatics Vienna (CIBIV), Max Perutz Labs, University of Vienna and Medical University of Vienna, Vienna BioCenter, Vienna, Austria.
Peter SchlögelhoferDepartment of Chromosome Biology, Max Perutz Labs, University of Vienna, Vienna BioCenter, Vienna, Austria. peter.schloegelhofer@univie.ac.at.ORCID 0000-0002-0909-3587
Max Perutz Labs · ATUniversity of Vienna · ATInstitute of Molecular Biotechnology · AT

Funding

Austrian Science Fund FWF I 2955
6 · The paper itself

Abstract

Despite vast differences between organisms, some characteristics of their genomes are conserved, such as the nucleolus organizing region (NOR). The NOR is constituted of multiple, highly repetitive rDNA genes, encoding the catalytic ribosomal core RNAs which are transcribed from 45S rDNA units. Their precise sequence information and organization remain uncharacterized. Here, using a combination of long- and short-read sequencing technologies we assemble contigs of the Arabidopsis NOR2 rDNA domain. We identify several expressed rRNA gene variants which are integrated into translating ribosomes in a tissue-specific manner. These findings support the concept of tissue specific ribosome subpopulations that differ in their rRNA composition and provide insights into the higher order organization of NOR2.

Indexed as

ArabidopsisChromosomes, Artificial, BacterialContig MappingDNA, PlantDNA, RibosomalGene LibraryGenome, PlantNucleolus Organizer RegionRibosomesRNA, RibosomalSequence Analysis, DNADNA, PlantDNA, RibosomalRNA, Ribosomal

Identifiers

PMID33452254
PMCPMC7810690
OpenAlexW3123381739

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.