Evidence map›Paper›PMID 33452238›Full record

ArticleNature communications2021

Irreversibility in dynamical phases and transitions.

Daniel S Seara, Benjamin B Machta, Michael P Murrell

Abstract read
In one paragraph

Article in Nature communications, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
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  4. Review
  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Daniel S SearaDepartment of Physics, Yale University, New Haven, CT, 06511, USA. daniel.seara@yale.edu.ORCID 0000-0001-5615-2888
Benjamin B MachtaDepartment of Physics, Yale University, New Haven, CT, 06511, USA. benjamin.machta@yale.edu.
Michael P MurrellDepartment of Physics, Yale University, New Haven, CT, 06511, USA. michael.murrell@yale.edu.ORCID 0000-0001-6788-2077

Funding

Systems analysis of phenotypic switch in control of cancer invasionU54CA209992 · NCI · YALE UNIVERSITY · PI LEVCHENKO, ANDRE · 2016 to 2021
$10.1M
Universal Roles of Force Generation and Transmission in Biological SystemsR01GM126256 · NIGMS · PURDUE UNIVERSITY · PI KIM, TAEYOON · 2017 to 2021
$2.3M
Physics and Systems Biology of Cellular DomainsR35GM138341 · NIGMS · YALE UNIVERSITY · PI MACHTA, BENJAMIN BROOKS · 2020 to 2024
$2.0M
NCI NIH HHS U54 CA209992NIGMS NIH HHS R01 GM126256NIGMS NIH HHS R35 GM138341
6 · The paper itself

Abstract

Living and non-living active matter consumes energy at the microscopic scale to drive emergent, macroscopic behavior including traveling waves and coherent oscillations. Recent work has characterized non-equilibrium systems by their total energy dissipation, but little has been said about how dissipation manifests in distinct spatiotemporal patterns. We introduce a measure of irreversibility we term the entropy production factor to quantify how time reversal symmetry is broken in field theories across scales. We use this scalar, dimensionless function to characterize a dynamical phase transition in simulations of the Brusselator, a prototypical biochemically motivated non-linear oscillator. We measure the total energetic cost of establishing synchronized biochemical oscillations while simultaneously quantifying the distribution of irreversibility across spatiotemporal frequencies.

Indexed as

EntropyModels, TheoreticalComputer SimulationNormal Distribution

Identifiers

PMID33452238
PMCPMC7810704

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.