Evidence map›Paper›PMID 33451994›Full record

ArticleArchives of disease in childhood2021

Indirect effects of the COVID-19 pandemic on paediatric healthcare use and severe disease: a retrospective national cohort study.

Thomas C Williams, Clare MacRae, Olivia V Swann, Haris Haseeb, Steve Cunningham, Philip Davies, Neil Gibson, Christopher Lamb, Richard Levin, Catherine M McDougall and 8 more

Open access · greenAbstract readMulticenter Study
In one paragraph

Article in Archives of disease in childhood, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
61citing papers in PubMed, 3 pooled it
8.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

61 citing papers in PubMed, 3 syntheses or guidelines pooled it, 100 citations in OpenAlex.

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1 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 3 institutions in 1 country.

Thomas C WilliamsDepartment of Paediatric Respiratory and Sleep Medicine, Royal Hospital for Sick Children, Edinburgh, UK.ORCID 0000-0002-3866-1344
Clare MacRaeUsher Institute, The University of Edinburgh, Edinburgh, UK.
Olivia V SwannDepartment of Child Life and Health, The University of Edinburgh, Edinburgh, UK.ORCID 0000-0001-7386-2849
Haris HaseebDepartment of Paediatric Respiratory and Sleep Medicine, Royal Hospital for Sick Children, Edinburgh, UK.
Steve CunninghamDepartment of Paediatric Respiratory and Sleep Medicine, Royal Hospital for Sick Children, Edinburgh, UK.
Philip DaviesDepartment of Paediatric Respiratory and Sleep Medicine, Royal Hospital for Children, Glasgow, UK.
Neil GibsonDepartment of Paediatric Respiratory and Sleep Medicine, Royal Hospital for Children, Glasgow, UK.ORCID 0000-0003-0136-1062
Christopher LambCritical Care, Royal Hospital for Children, Glasgow, UK.
Richard LevinCritical Care, Royal Hospital for Children, Glasgow, UK.
Catherine M McDougallDepartment of Paediatric Respiratory and Sleep Medicine, Royal Hospital for Sick Children, Edinburgh, UK.
Jillian McFadzeanCritical Care, Royal Hospital for Sick Children, Edinburgh, UK.
Ian PiperCritical Care, Royal Hospital for Sick Children, Edinburgh, UK.
Alastair TurnerCritical Care, Royal Hospital for Children, Glasgow, UK.
Stephen W TurnerDepartment of Child Health, University of Aberdeen, Aberdeen, UK.ORCID 0000-0001-8393-5060
Margrethe Van DijkeCritical Care, Royal Hospital for Sick Children, Edinburgh, UK.
Donald S UrquhartDepartment of Paediatric Respiratory and Sleep Medicine, Royal Hospital for Sick Children, Edinburgh, UK.ORCID 0000-0002-9048-9692
Bruce Guthrie *Usher Institute, The University of Edinburgh, Edinburgh, UK.
Ross J Langley *Department of Paediatric Respiratory and Sleep Medicine, Royal Hospital for Children, Glasgow, UK ross.langley@ggc.scot.nhs.uk.
Royal Hospital for Children · GBUniversity of Edinburgh · GBUniversity of Aberdeen · GB

Funding

Wellcome Trust
6 · The paper itself

Abstract

objectivesTo determine the indirect consequences of the COVID-19 pandemic on paediatric healthcare utilisation and severe disease at a national level following lockdown on 23 March 2020.

designNational retrospective cohort study.

settingEmergency childhood primary and secondary care providers across Scotland; two national paediatric intensive care units (PICUs); statutory death records.

participants273 455 unscheduled primary care attendances; 462 437 emergency department attendances; 54 076 emergency hospital admissions; 413 PICU unplanned emergency admissions requiring invasive mechanical ventilation; and 415 deaths during the lockdown study period and equivalent dates in previous years.

main outcome measuresRates of emergency care consultations, attendances and admissions; clinical severity scores on presentation to PICU; rates and causes of childhood death. For all data sets, rates during the lockdown period were compared with mean or aggregated rates for the equivalent dates in 2016-2019.

resultsThe rates of emergency presentations to primary and secondary care fell during lockdown in comparison to previous years. Emergency PICU admissions for children requiring invasive mechanical ventilation also fell as a proportion of cases for the entire population, with an OR of 0.52 for likelihood of admission during lockdown (95% CI 0.37 to 0.73), compared with the equivalent period in previous years. Clinical severity scores did not suggest children were presenting with more advanced disease. The greatest reduction in PICU admissions was for diseases of the respiratory system; those for injury, poisoning or other external causes were equivalent to previous years. Mortality during lockdown did not change significantly compared with 2016-2019.

conclusionsNational lockdown led to a reduction in paediatric emergency care utilisation, without associated evidence of severe harm.

Indexed as

PandemicsPopulation SurveillanceAdolescentChildChild, PreschoolCOVID-19Delivery of Health CareFemaleHospitalizationHumansInfantInfant, NewbornIntensive Care Units, PediatricMaleRetrospective StudiesSARS-CoV-2COVID-19epidemiologymortality

Identifiers

PMID33451994
PMCPMC8380881
OpenAlexW3118487423

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.